Role of the triacyl glycerol cycle. Summarize the cycle referring to the figure. What role does the cycle play in metabolism? Please be detailed in your answer CO₂ ++Oxaloacetate → Pyruvate H₂OKidneysa-Ketoglutarate Glucose -NH₂ExcretedAminoacids- UreaGlycogenUrea +AminoacidsProteinCori cycleAlanine-glucosecycleLactateAminoacids1Protein Glucose2GlucoseATP►MA→Pyruvate7Lactate DihydroxyacetonephosphateBrainGlycerol-3-PGlycerol5Fatty acidPyruvate Acetyl-CoAGlycogenLiverAcetyl-CoAPyruvateGlucoseKetonebodiesAcetyl-CoAATPFatty acidTriacylglycerolLpLTriacylglycerolcycle-Glycerol+SkeletalmuscleCO, + HOLpL3GlucosePyruvateAcetyl-CoA.Fatty acidHeartLpLGlycerolGlucoseATPDihydroxyacetonephosphateGlycerol-3-PGlycerolCO₂+H₂OAdiposetissueFatty acid TriacylglycerolFigure 19.9 The flux of metabolites between majortissues in the human body under normal homeostaticconditions is shown. The liver serves as the metabolichub of the body and coordinates the exchange ofmetabolites between major tissues and organs. Glucoseand triacylglycerols are the primary export products of tlliver under normal physiologic conditions and are used asources of energy for oxidative phosphorylation in mosttissues. Triacylglycerols in the blood are hydrolyzed bythe enzyme lipoprotein lipase (LpL) on the surface ofendothelial tissue to release free fatty acids and glycerolinto nearby tissues as shown here. Amino acids, ketonebodies, and lactate are usually found at relatively lowlevels in the blood, but they can be very importantmetabolites at times of limited food availability or intensphysical activity. See the text for details about the sixenumerated functions that are required to maintainmetabolic homeostasis.

Triacyclglycerol is a glycerol molecule esterified at its three hydroxyl groups by 3 fatty acid…

Answered: Role of the triacyl glycerol cycle.…

Role of the triacyl glycerol cycle. Summarize the cycle referring to the figure. What role does the cycle play in metabolism?

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Role of the triacyl glycerol cycle. Summarize the cycle referring to the figure. What role does the cycle play in metabolism? Please be detailed in your answer

CO₂ +
+
Oxaloacetate → Pyruvate H₂O
Kidneys
a-Ketoglutarate Glucose -
NH₂
Excreted
Amino
acids
- Urea
Glycogen
Urea +
Amino
acids
Protein
Cori cycle
Alanine-glucose
cycle
Lactate
Amino
acids
1
Protein Glucose
2
Glucose
ATP
►
MA
→Pyruvate
7
Lactate Dihydroxyacetone
phosphate
Brain
Glycerol-3-P
Glycerol
5
Fatty acid
Pyruvate Acetyl-CoA
Glycogen
Liver
Acetyl-CoA
Pyruvate
Glucose
Ketone
bodies
Acetyl-CoA
ATP
Fatty acid
Triacylglycerol
LpL
Triacylglycerol
cycle
-Glycerol+
Skeletal
muscle
CO, + HO
LpL
3
Glucose
Pyruvate
Acetyl-CoA.
Fatty acid
Heart
LpL
Glycerol
Glucose
ATP
Dihydroxyacetone
phosphate
Glycerol-3-P
Glycerol
CO₂
+
H₂O
Adipose
tissue
Fatty acid Triacylglycerol
Figure 19.9 The flux of metabolites between major
tissues in the human body under normal homeostatic
conditions is shown. The liver serves as the metabolic
hub of the body and coordinates the exchange of
metabolites between major tissues and organs. Glucose
and triacylglycerols are the primary export products of tl
liver under normal physiologic conditions and are used a
sources of energy for oxidative phosphorylation in most
tissues. Triacylglycerols in the blood are hydrolyzed by
the enzyme lipoprotein lipase (LpL) on the surface of
endothelial tissue to release free fatty acids and glycerol
into nearby tissues as shown here. Amino acids, ketone
bodies, and lactate are usually found at relatively low
levels in the blood, but they can be very important
metabolites at times of limited food availability or intens
physical activity. See the text for details about the six
enumerated functions that are required to maintain
metabolic homeostasis.

Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.

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