Radiopaque imaging agents are substances administered either orally or intrave- nously that absorb X-rays more strongly than body material. One of the best known of these is barium sulfate, the key ingredient in the so-called barium cocktail for imaging of the gastrointestinal tract. Among other X-ray contrast media are the so- called triiodoaromatics. You can get some idea of the imaging for which they are used from the following selection of trade names: Angiografin, Gastrografin, Cardiografin, Cholegrafin, Renografin, and Urografin. Following is a synthesis for diatrizoic acid from benzoic acid. СООН COOH COOH NO2 (3) NO2 O,N COOH COOH СООН I ICI 4 NH2 H,N NH2 H,N 'N' `N' I I H H Diatrizoic acid

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Aromatic Compounds

Aromatic organic compound or aromatic system is an important class of hydrocarbons under the branch of organic chemistry. Aromatic compounds are also called arenas. The definition of aromatic organic compounds can be stated as a class of organic compounds with a planar cyclic ring of atoms bonded through alternated single and double bonds. Due to these alternating bonds, a peculiar feature termed as ‘resonance’, that is, delocalization of pi electrons or the electrons is shared within the atoms of the ring which are present in the aromatic compounds. The word ‘aromatic’ includes a Greek word ‘aroma’ which means smell, indicating that they were named as such due to the sweet odor they produce. Many well-known flavors such as vanilla, cinnamon, and few scents from flowers are extracted from aromatic compounds. Benzene with chemical formula C6H6 is a very common aromatic compound that contains six atoms of carbon held in the cyclic ring of alternate double bonds. It is also to be noted that not all aromatic compounds contain benzene ring. This can be explained by Huckel’s rule.