The base-promoted rearrangement of an a-haloketone to a carboxylic acid, known as the Favorskii rearrangement, is illustrated by the conversion of 2-chlorocyclohexanone to cyclopentanecarboxylic acid. CI CO Na+ COH NaOH NaOH HCI THF THF H,O A proposed intermediate It is proposed that NaOH first converts the a-haloketone to the substituted cyclopropa- none shown in brackets and then to the sodium salt of cyclopentanecarboxylic acid.

Q: OCH3 FeBr3 , Br2 OCH3 Br

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Q: OH RCOCI „NH2 EtO OEt A Base H,0*

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Q: Propose a synthesis of the anti-inflammatory drug Fenclorac from phenylcyclohexane.

A: Fenclorac is an anti-inflammatory drug that is used during mild to severe inflammation. The…

Q: An α, β-unsaturated carbonyl compound can be prepared by a reaction known as a…

A: The given reaction is represented as follows:

Q: 3,5-Dibromo-4-hydroxybenzenesulfonic acid is used as a disinfectant. Propose a synthesis of this…

A: Phenol is reacted to concentrated sulfuric acid to give 4-hydroxybenzenesulfonic acid and…

Q: Propose mechanisms for the following base-catalyzed condensations, with dehydration.  benzaldehyde…

A: SOLUTION: Step 1: base catalyzed condensation (aldol condensation) of benzaldehyde and Propanal…

Q: hat steps are needed to convert benzene into p-isobutylacetophenone, a synthetic intermediate used…

A:

Q: 4) Show the mechanism for the acid catalyzed hydrolysis of the ketal shown below. H+, H₂O 요 + HO OH

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Q: From what aldehyde or ketone could each of the following be prepared by reduction with NaBH4 or…

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Q: Draw a mechanism for each of the three steps in the preparation of the 6-ethoxycarbonyl-…

A: Step:1

Q: OMe С101002 Mol. Wt.: 162.19 mp: 34-38ºc KOH MeOH CgHgO2 Mol. Wt.: 148.16 mp: 135°C ОН

A:

Q: Propose a mechanism to show how acetophenone undergoes base-promoted chlorinationto give…

A: These reaction is consider as substitution reaction in the presence of base

Q: Propose a mechanism for the acid-catalyzed hydrolysis of cyclohexanone dimethyl acetal.

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Q: CH3 CO₂Et Hagemann's ester The compound known as Hagemann's ester is prepared by treatment of a…

A:

Q: Propose a mechanism for conversion of 4-hydroxybenzaldehyde to A.

A: In case C- alkylation takes place .

Q: 7) Which of the following compounds cannot be prepared by an acetoacetic ester synthesis? Explain.…

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Q: To propose an intermediate and mechanism for the transformations

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Q: е. Cu2+ + OH

A: This reaction is called Benedict's Test.This given reaction can be shown below -

Q: Based on their structures and molecular weights, which of the four Claisen condensation products is…

A: In Claisen condensation beta-keto ester is formed while in aldol condensation, the beta-hydroxy…

Q: Sodium Borohydride Reduction of Ketones Compound Melting point Structure Color Benzil Benzoin 1,2-…

A: BENZIL M.P- 94.8 °C COLOR-yellow crystalline

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A: The functional group is a key component of a molecule that furnishes the characteristic chemical…

Q: Propose mechanisms for the Claisen condensation and aldol addition that comprise the first two steps…

A: The first two steps involved in the biosynthesis of isopentyl pyrophosphate are the conversion of…

Q: Specify whether the ketones below can be prepared by acetoacetic ester synthesis.

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Q: What products would result after hydrolysis from reaction of the enamine prepared from…

A: The question is based on organic reactions.We need to identify the product and explain its…

Q: Ethanolamine ammonia lyase, a coenzyme B12–requiring enzyme, catalyzes the following reaction.…

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Q: Propose a mechanism to explain how dimethyl sulfoxide and oxalyl chloride react to form the…

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Q: The trityl cation intermediate is a highly stable species due to the resonance stabilization…

A: Trityl cation also known as triphenylmethyl cation is very stable because the positive charge on…

Q: Propose a mechanism for acylation of benzene in the presence of aluminium chloride.

A: To solve this problem we have to write the mechanism of acylation reaction .

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A: An arrow always depicts from a region of high electron density to low electron density ; that is…

Q: Draw and explain the reaction mechanism for the following reaction:   cycloheptylamine +…

A:

Q: 3-metyl-2-butanol react with H₂SO₄ and continue with reductive ozonolysis process. What would become…

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Q: ) ezs Memyes 2) Hb O excess

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Q: i. H C=0 . Ag(NH,), + -ОН H,0

A: In this question the aldehyde given is benzaldehyde The reagent given is tollens reagent (Ammonical…

Q: Draw The SN2 mechanism pathway that takes place when metolachlor is reacted with HS-

A: In this question, HS- ion Attack by SN2 mechanism on Metolachlor.  You can see mechanism and…

Q: Propose a multi-step synthesis pathway to create the indicated products.

A: I - formation of acetylide ion from ethyl benzene  II - formation of 2-phenylbromoethane  III -…

Q: Propose a mechanism for conversion of the dianion to the ketone under mildly acidic conditions.

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Q: b) a) H3C. H3C 8- - (+/-) H3C. H3C -OH Br Br

A: We have find out the reagents for the given reaction.

Q: excess NaOH CI Propose a plausible mechanism for the following chemical transformation: O

A: is strong base abstract acidic proton.In  acts as nucleophile.

Q: Which product is formed as a result of the decarboxylation of the following molecule?

A: Decarboxylation- Removal of CO2 on heating or in the presence of NaOH+CaO (soda lime) from…

Q: Propose a mechanism for the biosynthesis of a-pinene from farnesyl pyrophosphate.

A: SInce  farnesyl pyrophosphate is present and we're following a biosynthesis and since farnesyl…

Aromatic Compounds

Aromatic organic compound or aromatic system is an important class of hydrocarbons under the branch of organic chemistry. Aromatic compounds are also called arenas. The definition of aromatic organic compounds can be stated as a class of organic compounds with a planar cyclic ring of atoms bonded through alternated single and double bonds. Due to these alternating bonds, a peculiar feature termed as ‘resonance’, that is, delocalization of pi electrons or the electrons is shared within the atoms of the ring which are present in the aromatic compounds. The word ‘aromatic’ includes a Greek word ‘aroma’ which means smell, indicating that they were named as such due to the sweet odor they produce. Many well-known flavors such as vanilla, cinnamon, and few scents from flowers are extracted from aromatic compounds. Benzene with chemical formula C6H6 is a very common aromatic compound that contains six atoms of carbon held in the cyclic ring of alternate double bonds. It is also to be noted that not all aromatic compounds contain benzene ring. This can be explained by Huckel’s rule.