(question from a test) Some post-translational modifications have the function of linking the protein to the plasma membrane. a) What is the common characteristics among all of them? Explain. b) Which one is functionally different? Explain.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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(question from a test)

Some post-translational modifications have the function of linking the protein to the plasma membrane.

a) What is the common characteristics among all of them? Explain.

b) Which one is functionally different? Explain.

Expert Solution
Step 1

Post-translational modifications are defined as the covalent chemical modifications made to proteins after the process of ribosomal translation.

Step 2

(a) Post-translational modifications will include phosphorylation, ubiquitination, glycosylation, nitrosylation, methylation, acetylation, lipidation and proteolysis. The common characteristic among different post-translational modifications is that they require an enzyme to catalyze the specific reaction. For example, phosphorylation requires enzyme protein kinase, proteolysis requires proteases, and so on.

(b)Post-translational modification that is functionally different is proteolysis because it is the breakdown of protein into their respective smaller polypeptides or amino acids. In contrast, all the other post-translational modifications are adding different substances or molecules to the proteins.

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