Answered: Why is a b-barrel as opposed to a…

Science

Biology

Why is a b-barrel as opposed to a b-sheet optimal for a transmembrane protein? Think about the energetics specifically.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 20QP: If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it...

See similar textbooks

Related questions

Q: Explain the binding problem.

A: The brain is one of the organs of the central nervous system, along with the spinal cord. It is…

Q: To release DNA from cells, detergent is used to disrupt the membranes of the cell and nucleus. What…

A: Membranes are primarily composed of a bilayer of lipids(fats). In addition to lipids, there are…

Q: 8) Indicate which of the five major types of membrane protein (adhesion, enzymatic, recognition,…

A: 1st Ans: Transmembrane protein

Q: Why chaperones are particularly important when translation occurs on membrane-bound ribosomes ?

A: Protein translation either occurs in cytosol by free ribosomes and some proteins gets translated on…

Q: The following figure shows the 3D structure of a tubulin dimer. A mutation in the beta tubulin…

A: Tubulin is a dimer consisting of two closely related polypeptides, α-tubulin and β-tubulin. Alpha-…

Q: PfCRT is found to have 10 peaks on a hydropathy plot given its primary sequence. Researchers also…

A: Proteins are linear polymers of amino acids attached to peptide bonds. Now the primary structure…

Q: What could happen to the proteins of cells treated with high amounts of free radicals that would…

A: The free radicals, such as superoxide anion (O2-) and hydroxyl radical (OH ), as well as the…

Q: Transport of histidine into a bacterial cell was measured at several different histidine…

A: The kinetics of transport of a molecule via a carrier protein and a protein channel differ from each…

Q: et’s suppose we have downloaded the structure of Hemoglobin from PDB. Now we want to retrieve the…

A: Understanding the three-dimensional structure of proteins is basic in bioinformatics since it gives…

Q: Mild, non-ionic detergents (like Triton X-100, with polar but uncharged regions that do not denature…

A: t-Octylphenoxypolyethoxyethanol or Polyethylene glycol tert-octylphenyl ether or simply Triton…

Q: Analyse and interpret the SCAM data in Fig. 1, and make a table (remember to include a legend) to…

A: SCAM (Substituted Cysteine Accessibility Method) is an analytical technique which is used to study…

Question

Why is a b-barrel as opposed to a b-sheet optimal for a transmembrane protein? Think about the energetics specifically.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Similar questions

The nuclear import of proteins larger than 40 kDa requires the presence of what amino acid sequence? Describe the mechanism of nuclear import. How are nuclear transport receptors able to get through the nuclear pore complex?
The amino acid of a transmembrane protein was analyzed with a hydrophobicity (Kite-Doolittle) plot as shown below. Based on the graph on the left below how many times does the protein predicted pass through the membrane? TIBS 15-MARCH 1990 RVMV. Raw format file: RVMV. Protein Length: 318 Check: 7395 4. RVMV. Raw format file: RVMV. Protein Length: 318 Check: 7395 3 3 2- 2 -2- --3 -2 50 100 150 200 250 300 50 100 150 200 250 300 Residue Number Residue Number Figure 2 Figure 4 The Kyte-Doolittle (KD)12 hydrophobicity plot (w 9) of the M-chain of Rsp. viridis. The Sieved-Kyte-Doolittle (SKD)* hydrophobicity plot (w = 9) of the M-chain of Rsp. viridis. 1 time 3 time 5 times 7 times Other Mesh Sieved
Transport of histidine into a bacterial cell was measured at several different histidine concentrations, see table below. Based on these data, is histidine uptake facilitated by a carrier or channel protein? a b Histidine (uM) 2.5 7 16 31 72 с Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. A carrier protein because it becomes saturated. A carrier protein because it does not become saturated. A channel protein because it becomes saturated. Transport (uM/min) d A channel protein because it does not become saturated. 42.5 119 240 490 1000 X Your answer
Maintaining nuclear RanGTP levels is critical for nucleo-cytoplasmic transport. Describe how mutations that disrupt RanGEF function would affect the movement of proteins coming in and going out of the nucleus.
What effect will phosphorylation have on the behaviour of a protein on a 2D gel? 1. The spot corresponding to phosphorylated protein will be in the same position as that of unphosphorylated one. 2. Phosphorylated protein will run slower in the second dimension (SDS PAGE). 3. Compared to the spot of unphosphorylated protein, the spot corresponding to phosphorylated protein will focus during separation in the first dimension in an area with lower pH. 4. There will be shifts during both separation stages. O 3 O 1 O 4 O 2
Is this statement true or false? exlain why
I need an example to study for an test
The amide hydrogen atoms of peptide bonds within proteins can exchange with protons in the solvent. In general, amide hydrogen atoms in buried regions of proteins and protein complexes exchange more slowly than those on the solvent-accessible surface do. Determination of these rates can be used to explore the proteinfolding reaction, probe the tertiary structure of proteins, and identify the regions of protein–protein interfaces. These exchange reactions can be followed by studying the behavior of the protein in solvent that has been labeled with deuterium ( ²H), a stable isotope of hydrogen. What two methods described in this chapter could be readily applied to the study of hydrogen– deuterium exchange rates in proteins?
Analyse and interpret the SCAM data in Fig. 1, and make a table (remember to include a legend) to indicate where each amino acid is located (cytoplasm, membrane, periplasm).
I am studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that you postulate has 4 transmembrane segments. What kind of experiment would allow me to test this hypothesis that there are 4 trans membrane segments?
A peripheral protein, which is not integral to the cell membrane, is also called: a multi-pass transmembrane protein (like band 3.0 protein) a single-pass transmembrane protein (like glycophorin A) a monolayer-associated protein (like the COX-1 protein) a protein-attached protein (like cytochrome c) a lipid-linked protein (like the Ras protein)
Discuss the general structure of the carrier proteins within our cells. Describe how theirstructure allows function.