Question 13Lantus differs from "normal" insulin in that:Select one:O a. The usual insulin molecule has been combined with zinc isophaneOb. Aglycine has been substituted in at A21, and two new arginiínes have been added as B31 and B32Oc. An aspartic acid has been substituted for proline at B28d. A"C-peptide" chain has been addedThe proline at B28 and the lysine at B29 have been reversed

Insulin is a hormone that our body synthesizes in order to keep our blood glucose levels within the…

Answered: Question 13 Lantus differs from…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question 4. Diabetes mellitus possesses a serious health challenge worldwide and there has been an increased awareness for self-monitoring and point of care testing. The development of self- monitoring of blood glucose (SMBG) is probably the most important advance in controlling diabetes since the discovery of insulin. c) Compare the sensitivity and accuracy of glucose meter with a spectrophotometer. d) Elaborate the limitation of glucose meter in diagnostic application? e) Examine the advantage of DNA based biosensor as compared to enzyme biosensor
Question 27 Thyroid stimulating hormone regulates the transcription of the gene for which of the following? A. lodothyronine deiodinase, type 1 (DIO1) B. Thyroid hormone receptor a C. Thyroid peroxidase OD. B adrenergic receptor O E. Cytochrome P450SCC
Question 28 Receptors for which of the following hormones activate AKT kinase as part of their signaling pathway? O A. Ghrelin B. Insulin-like growth factor 1 C. Parathyroid hormone O D. Angiotensin II O E. Estradiol
Question 42 S OD. Dihydrotestosterone OE. Epinephrine 1000800 Which hormone is most like prolactin inhibiting hormone with respect to synthesis, signaling, solubility and half-life? A. Calcitonin O B. Gastric inhibitory polypeptide ⒸC.Oxytocin
Question 35 Which of the following hormones is secreted in response to a simple endocrine input? O A. Luteinizing hormone B. Corticotropin releasing hormone O C. Oxytocin OD. Prolactin E. Parathyroid hormone
Incorrect Question 51 Which of the following is a long-lasting insulin preparation? Lente NPH Lantus
Question 13 An increase in the ratio of glucagon to insulin, as occurs during a prolonged fast, would do which of the following? a. increase liver glucose production b. increase adipose tissue lipolysis c. increase glycogen storage in muscle and liver a and b are both correct O a, b, andc are all correct
QUESTION 1 Insulin can have pleiotropic (wide ranging) effects in cells because • The Insulin receptor phosphorylates a family of substrates inside cells. • There are over 20 versions of the Insulin receptor expressed in vertebrates. • The Insulin receptor heterodimerizes with the GH and PRL receptors. • MRAP (membrane associated receptor proteins) couple the Insulin receptor to different effector pathways inside cells. QUESTION 2 Cholecystokinin (CCK) is accurately described by which of the following statements? • It is not a member of a peptide hormone superfamily. • It binds to a 1 TMS receptor that signals through guanylate cyclase. • It is sulphated on tyrosine residues for full activity. • It is proteolytically released from POMC by gut cells. QUESTION 3 Insulin ... • is released from the pancreas in vertebrates and invertebrates. • Is released from the vertebrate pancreas in response to hyperglycemia. • is released from the vertebrate pancreas in a response to hypoglycemia. •…
Question 4. Diabetes mellitus possesses a serious health challenge worldwide and there has been an increased awareness for self-monitoring and point of care testing. The development of self- monitoring of blood glucose (SMBG) is probably the most important advance in controlling diabetes since the discovery of insulin. a) Dextrostix, the first glucose meter was invented by Ernie Adams. Briefly discuss. b) There are three principles of enzymatic reactions, utilized by current glucose meters. Compare and briefly discuss these three principles.
Question 9 When would IGF-1 concentration in the blood stream be at its highest? O A. Immediately after a meal OB. In the absence of binding protein OC. When growth hormone concentration is at its lowest OD. During times of increased stress O E. At the peak of the pubertal growth spurt
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