Select all the correct statements. Note there might be more than 1 correct statement. Gluconeogenesis is the production of glucose from pyruvate Gluconeogenesis is the generation of glucose from non-carbohydrate sources Gluconeogenesis is the process by which one molecule of glucose is converted into two molecules of pyruvate Gluconeogenesis is a 10-step process to breakdown glucose into pyruvate Gluconeogenesis is a process that converts glycogen in to glucose
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- QUESTION 44 Gluconeogenesis can be described as "glycolysis backwards" but some enzymes are replaced by different enzymes in gluconeogenesis. Which of the following enzyme(s) is / are needed to replace pyruvate kinase? OA phosphogycerate mutase OB phosphoenolpyruvate carboxykinase Oc pyruvate carboxylase OD pyruvate dehydrogenase OE both B and C are needed to replace pyruvate kinase QUESTION 45 Oxaloacetate appears in multiple pathways in metabolism. Which of the following statements describing its role is incorrect? OA it will be converted to malate to be removed from the mitochondria to be used in gluconeogenesis in the faste state OB. it will be replenished by the action of pyruvate carboxylase in the fed state Ocit will condense to form citrate with acetyl CoA in the tricarboxylic acid cycle in the fed state O D.it will condense to form citrate with acetyl CoA in the tricarboxylic acid cycle in the fasted state OE none of the above statements (A, B, C, or D) are incorrectQuestion 9 If 14CO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? O Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V a Oxaloacetate b Citric acid Isocitric acid d a-Ketoglutarate e Succinyl-CoA f Succinate Fumarate h MalateQuestion 9 Match the enzyme with a phrase about it. v Catalyzes a substrate lovei phosphorylation 3. Pyruvate kinaise v breaks down sucrose to glucose and fructose b. phosphovylase e phosphohaxesa semerase (ato called giasose-6 phosphete samerane) v is a type of isomerase v removes one glucose residue from glycogen d. Sucrase A Muving to another question will save this response
- Question 7 Which of the following statements is CORRECT? The activity of the alpha(1,6)glucosidase produces a glucose-1-phosphate product. UDP-glucose pyrophosphorylase activated glucose-1-phosphate by producing UDP-glucose. Oa-Amylase digests glycogen by cleaving alpha(1,6) linkages to produce glucose- 6-phosphate and limit dextrins. Glycogen phosphatase removes the phosphate from glucose-1-phosphate to allow free glucose to be released into the blood. Question 8 Which of the following statements is CORRECT in response to epinephrine? There will be an increase in glycogen synthesis, gluconeogenesis, and amino acid metabolism with an increase in activity in the urea cycle. Protein phosphatase 1 will dephosphorylate acetyl-CoA synthetase resulting in increased production of mevalonate. The activation of phosphorylase kinase will activate glycogen synthase and inhibit the activity of glycogen phosphorylase. Protein kinase A activation will phosphorylate glycogen synthase to reduce its…Question 5 (1 point) Which of the following sequences correctly describes the overall process of metabolizing glucose? Pyruvate oxidation, Krebs cycle, glycolysis, electron transport, oxidative phos- phorylation Oxidative phosphorylation, Krebs cycle, pyruvate oxidation, glycolysis, electron transport Glycolysis, pyruvate oxidatioơn, Krebs cycle, electron transport, oxidative phosphorylation O Krebs cycle, oxidative phosphorylation, glycolysis, electron transport, pyruvate oxidationRemaining V Ha Question 17 Triose phosphate isomerase catalyzes the conversion of Glyceraldehyde-3- phosphate to Dihydroxyacetone phosphate. Glyceraldehyde-3-P Dihydroxyacetone phosphate The Km of this enzyme for its substrate Glyceraldehyde-3-phosphate is 1.8 x 10 M. When [Glyceraldehyde-3-phosphate] = 30 uM the rate of the reaction (v) was 82.5 umol/mL/sec and the Vmax was 132 umol/mL/sec. Assuming 3 nanomoles/mL of enzyme was used ([Eotal = 3 nanomol/mL) the kcat for this enzyme is: Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a 44000/sec b 1100/sec 88/min d. 120/hour e 11/min Im f 450000/sec g 52800/sec 175/sec
- Question 3: A runner just finished a marathon. For the enzymes listed below, indicate whether the enzyme activity is upregulated (1) or downregulated (↓) in the muscle and liver, respectively. Enzyme (a) Glycogen synthase (b) Phosphofructokinase-1 (c) Fructose-Bisphosphatase-2 (d) Pyruvate kinase (e) Pyruvate carboxylase (f) Acetyl-CoA carboxylase Muscle Livertrue or false 1.The so-called “adrenaline rush” promotes glycogenesis. 2. There are 4 irreversible steps in gluconeogenesis. 3. High amount of citrate decreases the activity of fructose 1,6-bisphosphatase. 4. Two molecules of ATP and 4 molecules of GTP are consumed to produce one molecule of glucose in gluconeogenesis. 5.Question:- Write two paragraphs that describe how phosphofructokinase-1 and fructose 1,6-bisphosphatase are regulated in a coordinated and reciprocal manner. The first paragraph should describe how the enzymes are regulated in response to energy needs in muscle cells. The second paragraph should describe how the hormones glucagon and insulin exert their effects via fructose 2,6-bisphosphate in liver cells.
- Question 6 Complete the following sentence (note there may be more than 1 correct response). Fructose 6-phosphate is: produced from pyruvate produced from glucose-6-phosphate in the presence of phosphohexose isomerase requires ATP to be converted into Fructose 1,6-bisphosphate produced from glucose-6-phosphate in the presence of phosphofructokinase-1QUESTION 34 Which of the following represents a reaction that could be used to refil the TCA cycle Aspartate -a -ketoglutarate Pyruvate Oxaloacetate O Oxaloacetate- Phosphoenol pyruvate Citrate - Oxaloacetate + acetyl COAQuestion 12 Which reaction in glycolysis consumes an inorganic phosphate (P₁)? O oxidation of glyceraldehyde 3-phosphate O isomerization of 1,3-biphosphoglycerate isomerization of glucose 6-phosphate O cleavage of glyceraldehydes 3-phosphate O phosphorylation of fructose 6-phosphate Prev