The CAMP formed by adenyl cyclase does not persist because 5- Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give 5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes the presence of the more active 'a' form of Glycogen Phosphorylase. a If no precautions are taken blood that has been stored for some time becomes depleted in 2-3 BPG which will result in increased binding of 02 to Hemoglobin with decreased release of 0, to tissues. Sickle-cell anemia is the consequence of HbS polymerization through hydrophobic contacts between the side chain Vala6 and a pocket in the EF corner of a-subunits. d. Decreasing the free energy of activation increase the reaction rate. The catalytic efficiency of an enzyme cannot exceed the diffusion rate e of encounters between E and S. f When [S] = Km the velocity = Vmax/2. Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the g hyperbolic Michaelis-Menten V vs. S plot into a straight line. According to the Michaelis-Menten equation the v/Vmax ratio = 0.4 when [S] = 4 Km: If Vmax = 100 umol/mL/sec and Km = 2 mM the velocity of the reaction i when [S] = 20 mM is 10 umol/mL/sec.
The CAMP formed by adenyl cyclase does not persist because 5- Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give 5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes the presence of the more active 'a' form of Glycogen Phosphorylase. a If no precautions are taken blood that has been stored for some time becomes depleted in 2-3 BPG which will result in increased binding of 02 to Hemoglobin with decreased release of 0, to tissues. Sickle-cell anemia is the consequence of HbS polymerization through hydrophobic contacts between the side chain Vala6 and a pocket in the EF corner of a-subunits. d. Decreasing the free energy of activation increase the reaction rate. The catalytic efficiency of an enzyme cannot exceed the diffusion rate e of encounters between E and S. f When [S] = Km the velocity = Vmax/2. Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the g hyperbolic Michaelis-Menten V vs. S plot into a straight line. According to the Michaelis-Menten equation the v/Vmax ratio = 0.4 when [S] = 4 Km: If Vmax = 100 umol/mL/sec and Km = 2 mM the velocity of the reaction i when [S] = 20 mM is 10 umol/mL/sec.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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![The CAMP formed by adenyl cyclase does not persist because 5-
Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give
5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes
the presence of the more active 'a' form of Glycogen Phosphorylase.
a
If no precautions are taken blood that has been stored for some time
becomes depleted in 2-3 BPG which will result in increased binding of
02 to Hemoglobin with decreased release of 0, to tissues.
Sickle-cell anemia is the consequence of HbS polymerization through
hydrophobic contacts between the side chain Vala6 and a pocket in
the EF corner of a-subunits.
d.
Decreasing the free energy of activation increase the reaction rate.
The catalytic efficiency of an enzyme cannot exceed the diffusion rate
e
of encounters between E and S.
When [S] = Km the velocity = Vmax/2.
Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the
g
hyperbolic Michaelis-Menten V vs. S plot into a straight line.
According to the Michaelis-Menten equation the v/Vmax ratio = 0.4
h
when [S] = 4 Km:
If Vmax = 100 umol/mL/sec and Km = 2 mM the velocity of the reaction
i
when [S] = 20 mM is 10 umol/mL/sec.
N](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd5cc39c9-8b2b-4beb-a3cb-5d1bdcb587ab%2Fb98e5175-0b56-4ec8-814a-47c4af02593c%2Fk4i8gy_processed.jpeg&w=3840&q=75)
Transcribed Image Text:The CAMP formed by adenyl cyclase does not persist because 5-
Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give
5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes
the presence of the more active 'a' form of Glycogen Phosphorylase.
a
If no precautions are taken blood that has been stored for some time
becomes depleted in 2-3 BPG which will result in increased binding of
02 to Hemoglobin with decreased release of 0, to tissues.
Sickle-cell anemia is the consequence of HbS polymerization through
hydrophobic contacts between the side chain Vala6 and a pocket in
the EF corner of a-subunits.
d.
Decreasing the free energy of activation increase the reaction rate.
The catalytic efficiency of an enzyme cannot exceed the diffusion rate
e
of encounters between E and S.
When [S] = Km the velocity = Vmax/2.
Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the
g
hyperbolic Michaelis-Menten V vs. S plot into a straight line.
According to the Michaelis-Menten equation the v/Vmax ratio = 0.4
h
when [S] = 4 Km:
If Vmax = 100 umol/mL/sec and Km = 2 mM the velocity of the reaction
i
when [S] = 20 mM is 10 umol/mL/sec.
N
![Question 15
Which of the following statements are TRUE?
O Multiple answers: Multiple answers are accepted for this question
Select one or more answers and submit. For keyboard navigation... SHOW MORE V
The CAMP formed by adenyl cyclase does not persist because 5'-
Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give
5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes
the presence of the more active 'a' form of Glycogen Phosphorylase.
a
If no precautions are taken blood that has been stored for some time
becomes depleted in 2-3 BPG which will result in increased binding of
O2 to Hemoglobin with decreased release of 0, to tissues.
Sickle-cell anemia is the consequence of HbS polymerization through
hydrophobic contacts between the side chain Vala6 and a pocket in
the EF corner of a-subunits.
d
Decreasing the free energy of activation increase the reaction rate.
The catalytic efficiency of an enzyme cannot exceed the diffusio ate
e
of encounters between E and S.
When [S] = Km the velocity = V,max/2.
Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the
g
nerbolic Michaelis Menten Vus
isht line](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd5cc39c9-8b2b-4beb-a3cb-5d1bdcb587ab%2Fb98e5175-0b56-4ec8-814a-47c4af02593c%2Fifjbjwi_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Question 15
Which of the following statements are TRUE?
O Multiple answers: Multiple answers are accepted for this question
Select one or more answers and submit. For keyboard navigation... SHOW MORE V
The CAMP formed by adenyl cyclase does not persist because 5'-
Phosphodiesterase activity prevalent in cells hydrolyzes CAMP to give
5'-AMP. Caffeine inhibits 5'-Phosphodiesterase activity which promotes
the presence of the more active 'a' form of Glycogen Phosphorylase.
a
If no precautions are taken blood that has been stored for some time
becomes depleted in 2-3 BPG which will result in increased binding of
O2 to Hemoglobin with decreased release of 0, to tissues.
Sickle-cell anemia is the consequence of HbS polymerization through
hydrophobic contacts between the side chain Vala6 and a pocket in
the EF corner of a-subunits.
d
Decreasing the free energy of activation increase the reaction rate.
The catalytic efficiency of an enzyme cannot exceed the diffusio ate
e
of encounters between E and S.
When [S] = Km the velocity = V,max/2.
Lineweaver-Burk double reciprocal (1/V vs. 1/S) plots convert the
g
nerbolic Michaelis Menten Vus
isht line
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