Propose an efficient synthetic route for the following transformations, showing the intermediate that each reagent leads to (not the mechanism - but the "in-between" products): a. HS
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- Devise a concise synthesis for the following transformations. Clearly show the reagent and productfor each step. Each synthesis can be accomplished in two stepsDraw a stepwise mechanism for the following reaction, which results in the synthesis of bisphenol F (R = H), an additive used in a variety of packaging materials. Bisphenol F is related to BPA (bisphenol A, R =CH3), a reagent used to harden some plastics, now removed from certain baby products because of its estrogen-like activity that can disrupt endocrine pathways.Draw a stepwise mechanism for the following reaction, one step in the synthesis of the cholesterol-lowering drug pitavastatin, marketed in Japan as a calcium salt under the name Livalo.
- Propose a possible reaction mechanism for the following transformation. Draw out the steps with the correct reaction arrows.Rank the following esters in order of decreasing reactivity in the first slow step of a nucleophilic acyl substitution reaction (formation of the tetrahedral intermediate):Rank the same esters in order of decreasing reactivity in the second slow step of a nucleophilic acyl substitution reaction (collapse of the tetrahedral intermediate).Draw a stepwise mechanism for the formation of A from an alcohol and acid chloride. A was converted in one step to blattellaquinone, the sex pheromone of the female German cockroach, Blattella germanica.
- Using your reaction roadmap as a guide, show how to convert cyclohexanol into racemic trans-1,2-cydohexanediol. Show all required reagents and all molecules synthesized along the way.Using your reaction roadmap as a guide, show how to convert cyclohexane into hexanedial. Show all reagents and all molecules synthesized along the way.Using your reaction roadmap as a guide, show how to convert butane into butanal. Show all reagents needed and all molecules synthesized along the way.
- Using your reaction roadmaps as a guide, show how to convert propane into propyl propanoate. You must use propane as the source of all carbon atoms in the target molecule. Show all reagents needed and all molecules synthesized along the way.Using your reaction roadmap as a guide, show how to convert 2-methylpentane into 2-methyl-3-pentanone. Show all reagents needed and all molecules synthesized along the way.Cyclohexene can be converted to 1-cyclopentenecarbaldehyde by the following series of reactions. Propose a structural formula for each intermediate compound.