Propose a reasonable biosynthesis for Compound 14 starting from Acetyl CoA, SAM, S- alanine, S-phenylalanine and ATP. CH CH 14
Q: Residue Asn 204 in the glucose binding site of hexokinase IV was mutated, in two separate experiment...
A: Hexokinase is the enzyme that catalyses the Phosphorylation of glucose to Glucose 6 phosphate in Gly...
Q: The following reactions were catalyzed by an enzyme that follows the Michaelis-Menten mechanism in t...
A: The given enzyme kinetics is said to follow Michaelis-Menten mechanism. Here Substrate concentration...
Q: What is the structure of intermediate F?
A: Metabolism is a biochemical reaction which is consisted of catabolic (breakdown) and anabolic (synth...
Q: Disulfide bridges are limited in that only one particular amino acid can form these types of interac...
A: Amino acids are building blocks of proteins and alpha carbon of amino acids consist of carboxylic gr...
Q: Malonyl-ACP is a precursor in fatty acid synthesis in the acyl carrier protein pathway. Draw the str...
A: Fatty acid synthesis is the formation of fatty acids from acetyl co A and NADH using fatty acid synt...
Q: How does adjusting Mg2+ concentration affect the PCR yield and specificity? How does adjusting prim...
A: Introduction: Polymerase chain reaction involves the ampliifcation of a particular piece of DNA to p...
Q: 5. Assume that you are trying to do a gel mobility shift experiment using a normal set of Trp genes....
A: The gel mobility shift assay is a biochemistry technique used to detect protein complexes with DNA. ...
Q: What biological rationale can explain why there are so few variants observed at position 65 of the h...
A: The iron atom in the heme group can form a total of 6 coordinate bonds . 4 of these are formed with ...
Q: It is becoming possible for molecular biologists to synthesizealmost any protein desired. Suppose yo...
A: Comparative physiology is a branch of physiology that investigates and exploits the wide range of fu...
Q: 3. Differentiate Enzyme Inhibition by filling the table below: Competitive Non-Competitive Uncompeti...
A: Enzyme inhibition is a process by which the activity of an enzyme is altered. Inhibitors are substan...
Q: What would be the pH level for an enzyme, that prefers acidic conditions.
A: The acidity or basicity of water is determined by its pH. The scale runs from 0 to 14, with 7 denoti...
Q: Tests Principle behind functional group that will give evidence of a References the test a positive ...
A: Generally carbohydrates are defined as polyhydroxy aldehydes or ketones . carbohydrates also are ca...
Q: 23. In the concerted model, the most active enzyme form will be when a. All subunits are in the R st...
A: Enzyme can have it's subunits in 2 conformations : Low-activity state -(Tense)T state High-activity...
Q: Make a graphical representation of activation energy and change of free energy in a reaction and com...
A: Enzymes are the substances that catalyse reactions by increasing the rate of reaction. They are usua...
Q: Lane 1 = TakaraBio 200 bp DNA ladder Lane 2 = Haell only; (thick band) 1883 bp and 1871 bp, 799 bp L...
A: Understanding the restriction digestion patterns of any plasmid is very important to know where enzy...
Q: Assessing the efficacy of glucosamine and chondroitin sulfate for arthritis pain Treatment with cho...
A: Glucosamine and chondroitin are two chemicals that exist naturally in your cartilage. Available in s...
Q: Which of the following Fischer structure is repres structure? CHOH
A: The Fischer and Haworth projection are the two different ways to represent the organic molecules. As...
Q: hospital, his physician told him that his infarction is the result of a long history of smoking. Exp...
A: Cholesterol is an important steroid required for many steroid synthesis like testosterone. It is pre...
Q: Typically, opiates have the ability to a. cause intense hallucinations. b. suppress the sensation of...
A: The correct answer is b. suppress the sensation of pain A drug that is used to relieve pain or induc...
Q: Under typical conditions, how many protons are pumped across the mitochondrial intermembrane for eac...
A: NADH is the electron carrier that transfers electrons to complex 1 in respiratory chain . In respons...
Q: In keeping a bottle of vegetable oil with no preservative, it must be coveredtightly and refrigerate...
A: Triacylglycerols are lipids present in oils that have a glycerol backbone with the three hydroxyl gr...
Q: Which of the following statements below is true?
A: Rock salt is a halite which is a mineral and form of common salt called as sodium chloride. This mi...
Q: The enzyme phosphofructokinase transfers a phosphate from ATP to the hydroxyl group a C1 of fructos...
A: Substrate specificity - The particular enzyme acts only on it's specific substrate and binds only to...
Q: sub= 18 help
A: The reaction given in the question involves the conversion of dihydroxyacetone phosphate to glyceral...
Q: What would be the consequence for actin filament assembly/disassembly if a mutation prevented actin’...
A: The kinetics of filament formation are modulated by ATP-binding on actin subunits, with ATP-binding ...
Q: -luginfile.php/7382296/mod_resource/content/0/Purine%20Practice%20Pathway.pdf 1 / 1 67% Purine Synth...
A: DNA and RNA are nucleic acids composed of nucleotides. Nucleotides are composed of a pentose sugar (...
Q: 70 degree Celcious is the melting point of stearic acid, and 4 degree Celcius is the melting point o...
A: Fatty acids (FA) are the building blocks of the fat present in our bodies or we eat. Fats breakdown ...
Q: Amount of water added (mL) Amount of Stock Solution (mL) Final Concentration A Solution 1 0. Solutio...
A: The concentration of unknown solution can be calculated from the formula C1V1= C2V2 Where C1= Concen...
Q: Write the net ATP in glyconeogenesis and write the net reaction of it...
A: Glyconeogenesis is the synthesis of sugars like glucose and glycogen from sources other than carbohy...
Q: Explain what is happening in point A in terms of the form of Alanine. What is point B? Explain what ...
A: Alanine is an Amino acid which consists of 2 acidic groups. Hence it is considered as diprotic Amino...
Q: (a) Vanillic acid is a phenolic compound found in vanilla and many other plant extracts. It is a fla...
A: According to shikimate pathway, Phenylalanine goes through biosynthesis wherein p-coumaroyl coenzym ...
Q: Calculate the net charge of the molecule at pH 3.
A: Amino acids are organic compounds with two functional group namely carboxyl and amino. Amino acids f...
Q: How many mL of 0.254 M NaOH are needed to fully react with 37.50 mL of 0.358 M H2SO4?
A: Concentration of the NaOH = 0.254 M Conc. of H2SO4 solution = 0.358 M or conc. of [H+]=2×0.358 M =0....
Q: Suppose you have a styrofoam insulating sphere with volumetric charge density. p. is 85.1 nC/m. If t...
A: Coulomb's law describes the electrostatic force between two charges. The force acts along the charge...
Q: The order of elution of amino acids X, Y, VW and Z in a cation exchanger eluted with a buffer of inc...
A: Ion exchange chromatography is used to separate molecules based on the charge. In the ion exchange c...
Q: What happens when cell division didn’t undergo or complete the Meiosis I and Meiosis II?
A: A process by which cell divide into two or more daughter cells and distributes its genetic material ...
Q: Three proteins K, L and M have the same % composition. Which is TRUE? A. The three proteins will ha...
A: Proteins are composed of a linear chain of amino acid sequences attached together via peptide bonds....
Q: Label all 5 the indicted regions in this coenzyme (labels like site of redox activity, etc)
A: Coenzyme are molecules which enhances or facilitates the action of specific enzyme. Enzymes are usu...
Q: In generating CO2, how can the citric acid cycle discriminate between the carbons in citrate given t...
A: In the first phase of the cycle, acetyl CoA combines with oxaloacetate, a four-carbon acceptor molec...
Q: As consequences to stopping drug use, headaches, nausea, shaking, and elevated blood pressure are al...
A: The group of symptoms that occurs on reduction in intake of drugs/ discontinuation ...
Q: glyceraldehyde-3-phosphate is synthesized with radioactive hydrogen and added to a solution containi...
A: Glycolysis is a catabolic pathway that converts glucose to pyruvate. It occurs in cytoplasm in serie...
Q: What are the complications of having a high blood glucose level?
A: Glucose is an essential nutrient for the growth and development of cells in most aerobic organisms. ...
Q: Given the active site and reaction mechanism below, what is the mechanism of rreversible inhibition ...
A: The mechanism followed by the given example is of Transition state analog Chemical compounds with a ...
Q: The amino acid histidine has been found to participate in both acid and base catalysis in many enzym...
A: Histidine is a basic amino acid and it contains an imidazole ring in its side-chain. Histidine is mo...
Q: Make a rough drawing of the ATP synthase machinery within the mitochondrial membrane and specificall...
A: F1F0-ATP synthase helps in synthesis of ATP in mitochondria. Proton influx into cytoplasm of mitocho...
Q: 3. Show a biological mechanism for the following retro process from the glyoxalate cycle. co.o OH
A:
Q: Which of the following is TRUE if pH is higher than the pka of the buffer? O [weak acid] approximate...
A: A buffer is a solution that is composed of a weak acid and its conjugate base. The pKa value is the ...
Q: You are given a suspension of purified mitochondria that are known to have adequate reserves of NAD+...
A: ATP synthesis occurs in the mitochondrial matrix by the ATP synthase enzyme. ATP synthase uses the p...
Q: Assigned Member of the Group of Alcohol Dehydrogenase and Lysozyme
A: Alcohol dehydrogenase is an enzyme that catalyses the conversion of ethanol to acetaldehyde. CH3-CH2...
Q: 5. Treatment of the patients with familial hypercholesterolemia by statins (pravastatin, for instant...
A: Familial hypercholesterolemia is an autosomal dominant condition. It is linked to early cardiovascu...
Step by step
Solved in 2 steps with 3 images
- Propose a reasonable biosynthesis for compound 34 starting from acetyl CoA, alanine CoA, malonyl CoA and valine methyl ester. H3C. CH3 H3C. CH3 CH3 34Propose a reasonable biosynthesis for Compound 14 starting from Acetyl CoA, SAM, S- alanine, S-phenylalanine and ATP. CHs CH3 14Identify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis. Carry your pathway as far as the rate-determining reaction in cholesterol biosynthesis. Drag the appropriate labels to their respective targets. succinyl-CoA succinate acetyl-CoA CoA-SH acetoacetyl-CoA HMG-CoA 2NADP 2NADPH+ 2H acetoacetate K UHL return to a mevalonate + CoA-SH
- Part A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodiesDraw the Conversion of Pyruvate to Acetyl CoA pathway and identify the different types of organic reaction mechanisms. Make sure to draw the structures of each biomolecule included in the pathway. Identify at most 5 organic reactions in the metabolic pathway.Outline the steps involved in the production of malonylCoA from acetyl-CoA.
- Describe the biochemical role of coenzyme Q10 and how supplementation may impact metabolism. Be sure to address the key terms listed below as part of your discussion; you may address additional etiologies as well. coenzyme Q Complex I Complex II Complex III ubiquinone ubiquinol Electron transport chain Oxidative phosphorylation Reactive oxygen speciesAll of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements? Group of answer choices The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesisDraw the Biosynthesis of fatty acids from Acetyl CoA pathway and identify the different types of organic reaction mechanisms. Make sure to draw the structures of each biomolecule included in the pathway. Identify at most 5 organic reactions in the metabolic pathway.
- C-CH2 + H* CO, + CH,-C-S-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase LigaseStarting with lactate, explain how phosphoenolpyruvate is produced. Include reactions of essential enzymes such as pyruvate carboxylase, and phosphoenolpyruvate carboxykinase. Explain the sites of action of these enzymes.What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Group of answer choices Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase