Prior to the development of detection assay for HIV in the blood supply, HCV was used as a proxy. That is to say, any donated blood found to be contaminated with HBV or HCV was also assumed to be HIV positive as well. What do you think was the rationale behind the use of HCV as an indicator of HIV? Do you think this was a reasonable approach at the time?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter7: Basic Clinical Microbiology
Section7.8: Tests For Sexually Transmitted Diseases
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Prior to the development of detection assay for HIV in the blood supply, HCV was used as a proxy. That is to say, any donated blood found to be contaminated with HBV or HCV was also assumed to be HIV positive as well. What do you think was the rationale behind the use of HCV as an indicator of HIV? Do you think this was a reasonable approach at the time?

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Step 1-Introduction

Viruses are non cellular pathogenic particles. They lack cellular components to survive on their own. They infect a host organism and use the host's cellular components to replicate, causing infection.

Unlike all living organisms, viral genome is not restricted to double stranded DNA. Viral genome can also be RNA (double or single stranded) or single stranded DNA.

Viral infections include hepatitis, Ebola, dengue, influenza, severe acute respiratory syndrome (SARS), etc. Viral infection cannot be treated with antibiotics. Antiviral medications have been produced to help combat viral infections.

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