Predict the possible genotypes and phenotypes (ratios) of the offspring if the following individuals from generation IV mated: 3 and 11

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Hi! I need some help with question 20 for this problem set.

  1. Predict the possible genotypes and phenotypes (ratios) of the offspring if the following individuals from generation IV mated: 3 and 11

 

Show your work using Punnett square(s).

A report in the New England Journal of Medicine (Seminar et al. 2003) relayed a discovery
about a heretofore unknown critical regulatory mechanism of mammalian puberty (sexual
maturation). This research investigation was initiated because a large extended family sought
medical attention for infertility. Six of the 19 offspring (4 men and 2 women) were affected. They
met the criteria for hypogonadism. Although the rest of their body and their brain had normally
matured, they exhibited undeveloped or underdeveloped external and internal genetalia and low
concentrations of sex hormones. The pedigree for this family is depicted below.
*Seminara et al. 2003. The GPR54 gene as a regulator of puberty. New England Journal of
Medicine, 349:1614-1627.
11
{
{
9⁹
0⁹
O. O
☐☐
O
0
12 13 14 15 16
A₂
-O-
Standard 4a - Transfer of genetic information to offspring
Standard 4b - Predict patterns of inheritance based on evidence.
16. State a claim as to whether the trait/condition displayed in the pedigree above is
dominant, recessive, incomplete dominant or co-dominant? Provide evidence from the
pedigree to support your claim.
17. Is the trait Autosomal or Sex-linked? Provide evidence from the pedigree to support your
claim.
18. What is/are the possible genotype(s) for individual 3 in generation IV?
19. What is/are the possible genotypes(s) for individuals 11 in generation IV?
20. Predict the possible genotypes and phenotypes (ratios) of the offspring if the following
individuals from generation IV mated: 3 and 11
Show your work using Punnett square(s).
Transcribed Image Text:A report in the New England Journal of Medicine (Seminar et al. 2003) relayed a discovery about a heretofore unknown critical regulatory mechanism of mammalian puberty (sexual maturation). This research investigation was initiated because a large extended family sought medical attention for infertility. Six of the 19 offspring (4 men and 2 women) were affected. They met the criteria for hypogonadism. Although the rest of their body and their brain had normally matured, they exhibited undeveloped or underdeveloped external and internal genetalia and low concentrations of sex hormones. The pedigree for this family is depicted below. *Seminara et al. 2003. The GPR54 gene as a regulator of puberty. New England Journal of Medicine, 349:1614-1627. 11 { { 9⁹ 0⁹ O. O ☐☐ O 0 12 13 14 15 16 A₂ -O- Standard 4a - Transfer of genetic information to offspring Standard 4b - Predict patterns of inheritance based on evidence. 16. State a claim as to whether the trait/condition displayed in the pedigree above is dominant, recessive, incomplete dominant or co-dominant? Provide evidence from the pedigree to support your claim. 17. Is the trait Autosomal or Sex-linked? Provide evidence from the pedigree to support your claim. 18. What is/are the possible genotype(s) for individual 3 in generation IV? 19. What is/are the possible genotypes(s) for individuals 11 in generation IV? 20. Predict the possible genotypes and phenotypes (ratios) of the offspring if the following individuals from generation IV mated: 3 and 11 Show your work using Punnett square(s).
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