Please explain what the resting membrane potential is and its value. Make sure you include all structures involved in the creation and maintenance of the resting membrane potential.  Explanation addressing the question above Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from -40 mV to -80 mV. The membrane potential has two basic functions as a battery and transmitting signals between different parts of a cell. In non-excitable cells, the membrane potential is held at a relatively stable value, called the resting potential. The resting membrane potential of a neuron is about -70 mV. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron. It is determined by concentration gradients of ions across the membrane and by membrane permeability to each type of ion. Structure and molecules involved in the creation of the resting membrane potential are Resting K+ channels are responsible for generating the resting potential across the membrane, voltage-gated channels are responsible for propagating action potentials along the axonal membrane, two types of ion channels in dendrites and cell bodies are responsible for generating electric signals in postsynaptic cells. One type has a site for binding a specific extracellular neurotransmitter. The other type is coupled to a neurotransmitter receptor via a G-protein. That occurs because the effect of the charge is hugely greater than the effect of concentration. Maintenance of the resting potential is metabolically costly for a cell because of the active pumping of ions to counteract losses due to leakage. The reduced leakage currents show that there is a little need for active pumping in order to compensate and therefore low metabolic cost.   Question: please respond to the explanation above addressing the question on resting membrane potential

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Please explain what the resting membrane potential is and its value. Make sure you include all structures involved in the creation and maintenance of the resting membrane potential. 

Explanation addressing the question above

Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from -40 mV to -80 mV. The membrane potential has two basic functions as a battery and transmitting signals between different parts of a cell. In non-excitable cells, the membrane potential is held at a relatively stable value, called the resting potential. The resting membrane potential of a neuron is about -70 mV. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron. It is determined by concentration gradients of ions across the membrane and by membrane permeability to each type of ion. Structure and molecules involved in the creation of the resting membrane potential are Resting K+ channels are responsible for generating the resting potential across the membrane, voltage-gated channels are responsible for propagating action potentials along the axonal membrane, two types of ion channels in dendrites and cell bodies are responsible for generating electric signals in postsynaptic cells. One type has a site for binding a specific extracellular neurotransmitter. The other type is coupled to a neurotransmitter receptor via a G-protein. That occurs because the effect of the charge is hugely greater than the effect of concentration. Maintenance of the resting potential is metabolically costly for a cell because of the active pumping of ions to counteract losses due to leakage. The reduced leakage currents show that there is a little need for active pumping in order to compensate and therefore low metabolic cost.

 

Question: please respond to the explanation above addressing the question on resting membrane potential

 

 

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