Part A: Hypothesis Testing for Mode of Inheritance Section 1 Begin Jun 23, due July 8 11:59pm. Graded feedback July 15. Total marks 23 Data set A summarizes F2 numbers from an F1 cross arising from two, true-breeding Drosophila strains (P generation), which differ with respect to two mutant traits. The genes can be autosomal or X-linked and the mutant alleles can be dominant or recessive or incompletely or co-dominant. For Section 1 of part A do the following in the order given: a) Attach your data set to your report so that we know which cross you were given. 1 mark A Wt males purple body females purple body males purple body, no body stripes females purple body, no body stripes males no body stripes males B a++ 3028 +++ 302 ++C 1355 observed +b+ 1940 1079 2199 ab+ 1404 1061 a+c 1991 6517 abc 309 3243 3278 +bc 3073 b) Produce a genetic hypothesis about the mode of inheritance of each of the alleles from your data set. 1 mark per allele 4 marks You must come up with a hypothesis that both makes sense and will not be rejected, in other words, you need a hypothesis that will corroborate the experimental observations. c) Explain/describe how the data set seems to support your genetic hypothesis for each trait. For example, explain why you think a trait is recessive vs dominant or X-linked vs autosomal. To do this, you could comment on the observed ratios and/or differences or similarities in male and female numbers and explain how these provide support for your hypotheses. 2 marks per gene/trait = 4 marks d) Assign genetic symbols to the four alleles involved. Be sure your allele notations are informative. For example, use upper case to indicated dominance and lowercase to indicate recessive. If you use the superscript "+" it only tells the reader the allele is wildtype and not its dominance status. Be sure to review the posted video on LEARN to review how to assign meaningful alleles. 1 mark for each allele = 4 marks e) Illustrate how each of your genetic hypotheses is supported by the data. Show this using Punnett squares for each F1 cross and resulting F2 generation. Be sure all genotypes and phenotypes are clearly indicated directly within the Punnett or branching diagram. Separately analyze each gene. 3 marks each gene = 6 marks for 2 genes f) Indicate the expected (predicted) phenotypic numbers for the F2 generation from your Punnett square constructed in e) above. 1 mark per gene = 2 marks

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Part A: Hypothesis Testing for Mode of Inheritance
Section 1 Begin Jun 23, due July 8 11:59pm. Graded feedback July 15.
Total marks 23
Data set A summarizes F2 numbers from an F1 cross arising from two, true-breeding
Drosophila strains (P generation), which differ with respect to two mutant traits. The genes
can be autosomal or X-linked and the mutant alleles can be dominant or recessive or
incompletely or co-dominant. For Section 1 of part A do the following in the order given:
a) Attach your data set to your report so that we know which cross you were given.
1 mark
A
Wt males
purple body females
purple body males
purple body, no body stripes females
purple body, no body stripes males
no body stripes males
B
a++
3028
+++
302
++C
1355
observed
+b+
1940
1079
2199
ab+
1404
1061
a+c
1991
6517
abc
309
3243
3278
+bc
3073
b) Produce a genetic hypothesis about the mode of inheritance of each of the alleles from
your data set. 1 mark per allele 4 marks
You must come up with a hypothesis that both makes sense and will not be rejected,
in other words, you need a hypothesis that will corroborate the experimental
observations.
c) Explain/describe how the data set seems to support your genetic hypothesis for each
trait. For example, explain why you think a trait is recessive vs dominant or X-linked vs
autosomal. To do this, you could comment on the observed ratios and/or differences
or similarities in male and female numbers and explain how these provide support for
your hypotheses. 2 marks per gene/trait = 4 marks
d) Assign genetic symbols to the four alleles involved. Be sure your allele notations are
informative. For example, use upper case to indicated dominance and lowercase to
indicate recessive. If you use the superscript "+" it only tells the reader the allele is
wildtype and not its dominance status. Be sure to review the posted video on LEARN
to review how to assign meaningful alleles. 1 mark for each allele = 4 marks
e) Illustrate how each of your genetic hypotheses is supported by the data. Show this
using Punnett squares for each F1 cross and resulting F2 generation. Be sure all
genotypes and phenotypes are clearly indicated directly within the Punnett or
branching diagram. Separately analyze each gene. 3 marks each gene = 6 marks
for 2 genes
f) Indicate the expected (predicted) phenotypic numbers for the F2 generation from your
Punnett square constructed in e) above. 1 mark per gene = 2 marks
Transcribed Image Text:Part A: Hypothesis Testing for Mode of Inheritance Section 1 Begin Jun 23, due July 8 11:59pm. Graded feedback July 15. Total marks 23 Data set A summarizes F2 numbers from an F1 cross arising from two, true-breeding Drosophila strains (P generation), which differ with respect to two mutant traits. The genes can be autosomal or X-linked and the mutant alleles can be dominant or recessive or incompletely or co-dominant. For Section 1 of part A do the following in the order given: a) Attach your data set to your report so that we know which cross you were given. 1 mark A Wt males purple body females purple body males purple body, no body stripes females purple body, no body stripes males no body stripes males B a++ 3028 +++ 302 ++C 1355 observed +b+ 1940 1079 2199 ab+ 1404 1061 a+c 1991 6517 abc 309 3243 3278 +bc 3073 b) Produce a genetic hypothesis about the mode of inheritance of each of the alleles from your data set. 1 mark per allele 4 marks You must come up with a hypothesis that both makes sense and will not be rejected, in other words, you need a hypothesis that will corroborate the experimental observations. c) Explain/describe how the data set seems to support your genetic hypothesis for each trait. For example, explain why you think a trait is recessive vs dominant or X-linked vs autosomal. To do this, you could comment on the observed ratios and/or differences or similarities in male and female numbers and explain how these provide support for your hypotheses. 2 marks per gene/trait = 4 marks d) Assign genetic symbols to the four alleles involved. Be sure your allele notations are informative. For example, use upper case to indicated dominance and lowercase to indicate recessive. If you use the superscript "+" it only tells the reader the allele is wildtype and not its dominance status. Be sure to review the posted video on LEARN to review how to assign meaningful alleles. 1 mark for each allele = 4 marks e) Illustrate how each of your genetic hypotheses is supported by the data. Show this using Punnett squares for each F1 cross and resulting F2 generation. Be sure all genotypes and phenotypes are clearly indicated directly within the Punnett or branching diagram. Separately analyze each gene. 3 marks each gene = 6 marks for 2 genes f) Indicate the expected (predicted) phenotypic numbers for the F2 generation from your Punnett square constructed in e) above. 1 mark per gene = 2 marks
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