What is the probability that III-j has Huntington's? 3. Huntington disease is a late-onset disease caused by a single, dominant mutation. The followingpedigree is for a family with a history of Huntington disease. Those individuals who are alreadysuffering from the disease are shaded black. However, some additional individuals in generations II andIll also have the Huntington allele and will develop Huntington disease but have not yet shownsymptoms. Assume that individuals marrying into the family have no history of Huntington disease (thatis, they are homozygous recessive for the gene). Also assume that the diseased male in generation I isheterozygous for the gene and his wife is homozygous recessive.IIIIIIabcdefghijklm

To solve this problem, we need to calculate the probability that individual III-j in the pedigree…

Answered: 3. Huntington disease is a late-onset…

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter19: Introduction To Genetics

Section: Chapter Questions

Problem 9CT

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In cats, the genotype AA produces tabby fur color; Aa is also a tabby, and aa is black. Another gene at a different locus is epistatic to the gene for fur color. When present in its dominant W form (WW or Ww), this gene blocks the formation of fur color and all the offspring are white; ww individuals develop normal fur color. What fur colors, and in what proportions, would you expect from the cross AaWw Aa Ww?
In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor recessive gene. If 2 normal parents had a daughter with the symptoms ofthis disease, and a normal son, what is the probability that he might be acarrier of the recessive gene?Express answer in fraction form.
6. A person is simultaneously heterozygous for two autosomal genetic traits. One is a recessive condition foralbinism (alleles A and a); this albinism gene is foundnear the centromere on the long arm of an acrocentricautosome. The other trait is the dominantly inheritedHuntington disease (alleles HD and HD+). TheHuntington gene is located near the telomere of oneof the arms of a metacentric autosome. Draw all copies of the two relevant chromosomes in this person asthey would appear during metaphase of (a) mitosis,(b) meiosis I, and (c) meiosis II. In each figure, labelthe location on every chromatid of the alleles forthese two genes, assuming that no recombinationtakes place.
1 pts The pedigree below shows the expression of Huntington's disease in a family. Huntington's disease is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. It deteriorates a person's physical and mental abilities usually during their prime working years and has no cure. Huntington's is inherited as a dominant allele (H). Examine the pedigree below and determine the genotype for individual "2" DODO0O 2. O HH O Hh О h O either HH or Hh
6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.
5) Humans who have an abnormally high level of cholesterol are said to suffer from familialhypercholesterolemia.  The gene for this disorder is dominant (C). A man who isheterozygous for familial hypercholesterolemia marries a woman who is homozygousfor the recessive allele. What is the probability that they will have children that sufferfrom this disorder? please draw the puutnet square and also write the parents and gemtaics top the puutnet square thanks
1. Hair or fur length in cats is controlled by a single, autosomal gene; the short hair-allele is dominant to the allele for long hair. Hair color is produced by a different gene which is located on the X chromosome. One allele for this sex-linked gene produces yellow, while an alternate allele produces black fur color; individualswhich are heterozygous for these alleles are calico or tortiseshell in color.If a long-haired, black male is mated with a calico female homozygous for short hair what kind of kittens will be produced in the Ej generation? Give both genotypes and phenotypes; express the genotypes bothsymbolically and in words. Label answers clearly!!
BIU A- == 三E 12 - Match each of the following examples to the appropriate type of non-Mendelian inheritance. 1. A homozygous recessive genotype for the gene that encodes phenylalanine hydroxylase (which breaks down the amino acid phenylalanine) causes lighter skin color, a musty odor, differences in intellectual development, and seizures. 2. In pea plants, alleles of Gene W control flower color, with the dominant allele (W) leading to purple flower.color, and the recessive allele (w) leading to white flower color. Usually, a genotype of WW or Ww leads to purple flowers. However, when Gene C is homozygous recessive, WW or Ww plants always have white flowers. 3. In mallard ducks, feather coloring is controlled by Gene F. A dominant allele (F) leads to green head feathers, while a recessive allele (f) leads to brown head feathers. In male mallards, inheritance of one or more F alleles always leads to the green head feather trait. But female mallards always have brown head feathers,…
3. In the family pedigree shown in the following chart, an abnormal trait is inherited as a simple recessive. Unless there is evidence to the contrary, assume that the individuals who have married into this family do not carry the recessive gene for the trait. Colored squares and circles represent expressions of the trait (see figure). Calculate the probability of the trait appearing in a given offspring if the following cousins and second cousins in generations III and IV should marry:_ (a) III-1 x III-12; (b) III-4 x III-14; (c) III-6 x II-13: (d) IV-1 x IV-2 2 3 10 11 12 13 14 15 16 IV 2
1. A man and both his parents are affected with a disease. His older sister is unaffected. This man marries a woman who is also affected with this disease. Her father is affected, but her mother and younger brother are unaffected. Assume that this disease is caused by a single gene with two alleles with complete dominance. Draw the pedigree of the family above using the correct symbols and numbering. (3) What is the chance that the couple will produce an unaffected child? Please show your calculations
2. a. A Drosophila male from a true-breeding stockwith scabrous eyes was mated with a female from atrue-breeding stock with javelin bristles. Both scabrous eyes and javelin bristles are autosomal recessive mutant traits. The F1 progeny all had normaleyes and bristles. F1 females from this cross weremated with males with both scabrous eyes andjavelin bristles. Write all the possible phenotypicclasses of the progeny that could be produced from the cross of the F1 females with the scabrous, javelin males, and indicate for each class whether it is arecombinant or parental type.b. The cross in part (a) yielded the following progeny:77 scabrous eyes and normal bristles; 76 wild type(normal eyes and bristles); 74 normal eyes andjavelin bristles; and 73 scabrous eyes and javelinbristles. Are the genes governing these traits likelyto be linked, or do they instead assort independently? Why?c. Suppose you mated the F1 females from the crossin part (a) to wild-type males. Why would thiscross fail…
1. Muscular dystrophy is a sex-linked recessive condition. If a woman who does not have the conditions but is a carrier of the allele has a child with a normal male, what percentage of their daughters could have muscular dystrophy? What percentage of their sons could have muscular dystrophy? ) 2. What is the likely genotype and phenotype of a mom and dad who have a son with blue eyes and a daughter with brown eyes? The father has blue eyesShow a Punnett square to prove your answer.

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