I I Part I: Mendelian Inheritance Colour blindness is an X-linked recessive disorder characterized by the inability to either differentiate between colours or see colour at all. Cystic fibrosis is an autosomal recessive disorder characterized by the abnormal secretion of thick mucuses rather than thin. The resulting thick mucus can cause adverse effects in the lungs, pancreas, liver, kidneys, and intestines. Often men afflicted by this condition are rendered infertile. Gideon is colour blind and is a carrier for cystic fibrosis and his partner Malenia, is a carrier for both colour blindness and cystic fibrosis. Gideon and Malenia have 4 offspring; Sellen, Irina, Alexander, and Kenneth. Sellen is a carrier for colour blindness and has cystic fibrosis. Irina has colour blindness and is a carrier for cystic fibrosis. Alexander does not carry the mutation for colour blindness but is a carrier of cystic fibrosis. Finally, Kenneth is both colour blind and is afflicted by cystic fibrosis. Using the information provided to you above, answer the following questions regarding the family's genetics. Use the following notation to answer all questions: Individuals with colour blindness are delineated by Xb, whereas XB is used for individuals without colour blindness. Individuals with cystic fibrosis are delineated by f, while those without cystic fibrosis are delineated by F. 1. What are the genotypes of Gideon and Malenia ? 2. What are the genotypes of Sellen, Irina, Alexander, and Kenneth ?

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I
1
Part I: Mendelian Inheritance
Colour blindness is an X-linked recessive disorder characterized by the inability to either
differentiate between colours or see colour at all. Cystic fibrosis is an autosomal recessive
disorder characterized by the abnormal secretion of thick mucuses rather than thin. The
resulting thick mucus can cause adverse effects in the lungs, pancreas, liver, kidneys, and
intestines. Often men afflicted by this condition are rendered infertile. Gideon is colour blind
and is a carrier for cystic fibrosis and his partner Malenia, is a carrier for both colour blindness
and cystic fibrosis. Gideon and Malenia have 4 offspring; Sellen, Irina, Alexander, and Kenneth.
Sellen is a carrier for colour blindness and has cystic fibrosis. Irina has colour blindness and is a
carrier for cystic fibrosis. Alexander does not carry the mutation for colour blindness but is a
carrier of cystic fibrosis. Finally, Kenneth is both colour blind and is afflicted by cystic fibrosis.
Using the information provided to you above, answer the following questions regarding the
family's genetics.
Use the following notation to answer all questions: Individuals with colour blindness are
delineated by Xb, whereas XB is used for individuals without colour blindness. Individuals with
cystic fibrosis are delineated by f, while those without cystic fibrosis are delineated by F.
1. What are the genotypes of Gideon and Malenia
?
2. What are the genotypes of Sellen, Irina, Alexander, and Kenneth
?
Transcribed Image Text:I 1 Part I: Mendelian Inheritance Colour blindness is an X-linked recessive disorder characterized by the inability to either differentiate between colours or see colour at all. Cystic fibrosis is an autosomal recessive disorder characterized by the abnormal secretion of thick mucuses rather than thin. The resulting thick mucus can cause adverse effects in the lungs, pancreas, liver, kidneys, and intestines. Often men afflicted by this condition are rendered infertile. Gideon is colour blind and is a carrier for cystic fibrosis and his partner Malenia, is a carrier for both colour blindness and cystic fibrosis. Gideon and Malenia have 4 offspring; Sellen, Irina, Alexander, and Kenneth. Sellen is a carrier for colour blindness and has cystic fibrosis. Irina has colour blindness and is a carrier for cystic fibrosis. Alexander does not carry the mutation for colour blindness but is a carrier of cystic fibrosis. Finally, Kenneth is both colour blind and is afflicted by cystic fibrosis. Using the information provided to you above, answer the following questions regarding the family's genetics. Use the following notation to answer all questions: Individuals with colour blindness are delineated by Xb, whereas XB is used for individuals without colour blindness. Individuals with cystic fibrosis are delineated by f, while those without cystic fibrosis are delineated by F. 1. What are the genotypes of Gideon and Malenia ? 2. What are the genotypes of Sellen, Irina, Alexander, and Kenneth ?
Fall 2022
Lab 4 Analytical - Information Transfer & Inheritance
3. Construct a dihybrid cross showing the possible genotypes of Gideon and Malenia's
offspring
4. Based on the dihybrid cross you constructed in the previous question, state the probabilities
(as a percentage) of Gideon and Malenia's having offspring with the phenotypes below,
a. An offspring without genetic mutations (i.e. normal vision and homozygous dominant
for cystic fibrosis).
b. An offspring with cystic fibrosis.
c. Sellen being a carrier for colour blindness and had cystic fibrosis.
d. Irina having colour blindness and being a carrier for cystic fibrosis.
BIOL 1103
e. Alexander having normal vision and being a carrier for cystic fibrosis.
f. Kenneth being afflicted by both colour blindness and cystic fibrosis.
106
IIIIIII
Transcribed Image Text:Fall 2022 Lab 4 Analytical - Information Transfer & Inheritance 3. Construct a dihybrid cross showing the possible genotypes of Gideon and Malenia's offspring 4. Based on the dihybrid cross you constructed in the previous question, state the probabilities (as a percentage) of Gideon and Malenia's having offspring with the phenotypes below, a. An offspring without genetic mutations (i.e. normal vision and homozygous dominant for cystic fibrosis). b. An offspring with cystic fibrosis. c. Sellen being a carrier for colour blindness and had cystic fibrosis. d. Irina having colour blindness and being a carrier for cystic fibrosis. BIOL 1103 e. Alexander having normal vision and being a carrier for cystic fibrosis. f. Kenneth being afflicted by both colour blindness and cystic fibrosis. 106 IIIIIII
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