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Part 2: Molecular Weights The molecular weight of a large polymer such as a nucleic acid or a polypeptide depends on the length of the polymer. The monomers (nucleotides or amino acids) vary in molecular weight, but for a long polymer you can just use the average mass of a monomer, according to the table below: Double-stranded DNA (dsDNA) 618 Daltons/nucleotide pair Single-stranded DNA (ssDNA) 309 Daltons/nucleotide Single-stranded RNA (ssRNA) 320 Polypeptide 110 Daltons/nucleotide Daltons/amino acid Daltons are more or less the same as the atomic mass units you use in chemistry class: 1 Dalton 1 gram/mole Since macromolecules are large, the actual units used are usually kilo Daltons (KD). For the following questions, show your calculations. Use scientific notation where appropriate, and use appropriate units (micrograms, nanograms, etc). Round off your answers to three significant figures. a) Green Fluorescent Protein (GFP) is composed of a single polypeptide, 238 amino acids long. What is the approximate molecular weight of GFP in KD? b) What is the approximate molecular weight (in KD) of the coding region of the mRNA that encodes GFP? c) What is the approximate molecular weight of the corresponding double-stranded coding region of the DNA? d) What is the approximate ratio of the molecular weight of the coding region of the DNA to the molecular weight of the protein it encodes? (Show ALL your calculations on a piece of paper, take a picture and paste it in the space below).

Part 2: Molecular Weights The molecular weight of a large polymer such as a nucleic acid or a polypeptide depends on the length of the polymer. The monomers (nucleotides or amino acids) vary in molecular weight, but for a long polymer you can just use the average mass of a monomer, according to the table below: Double-stranded DNA (dsDNA) 618 Daltons/nucleotide pair Single-stranded DNA (ssDNA) 309 Daltons/nucleotide Single-stranded RNA (ssRNA) 320 Polypeptide 110 Daltons/nucleotide Daltons/amino acid Daltons are more or less the same as the atomic mass units you use in chemistry class: 1 Dalton 1 gram/mole Since macromolecules are large, the actual units used are usually kilo Daltons (KD). For the following questions, show your calculations. Use scientific notation where appropriate, and use appropriate units (micrograms, nanograms, etc). Round off your answers to three significant figures. a) Green Fluorescent Protein (GFP) is composed of a single polypeptide, 238 amino acids long. What is the approximate molecular weight of GFP in KD? b) What is the approximate molecular weight (in KD) of the coding region of the mRNA that encodes GFP? c) What is the approximate molecular weight of the corresponding double-stranded coding region of the DNA? d) What is the approximate ratio of the molecular weight of the coding region of the DNA to the molecular weight of the protein it encodes? (Show ALL your calculations on a piece of paper, take a picture and paste it in the space below).

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Part 2: Molecular Weights The molecular weight of a large polymer such as a nucleic acid or a polypeptide depends on the length of the polymer. The monomers (nucleotides or amino acids) vary in molecular weight, but for a long polymer you can just use the average mass of a monomer, according to the table below: Double-stranded DNA (dsDNA) 618 Daltons/nucleotide pair Single-stranded DNA (ssDNA) 309 Daltons/nucleotide Single-stranded RNA (ssRNA) 320 Polypeptide 110 Daltons/nucleotide Daltons/amino acid Daltons are more or less the same as the atomic mass units you use in chemistry class: 1 Dalton 1 gram/mole Since macromolecules are large, the actual units used are usually kilo Daltons (KD). For the following questions, show your calculations. Use scientific notation where appropriate, and use appropriate units (micrograms, nanograms, etc). Round off your answers to three significant figures. a) Green Fluorescent Protein (GFP) is composed of a single polypeptide, 238 amino acids long. What is the approximate molecular weight of GFP in KD? b) What is the approximate molecular weight (in KD) of the coding region of the mRNA that encodes GFP? c) What is the approximate molecular weight of the corresponding double-stranded coding region of the DNA? d) What is the approximate ratio of the molecular weight of the coding region of the DNA to the molecular weight of the protein it encodes? (Show ALL your calculations on a piece of paper, take a picture and paste it in the space below).
Transcribed Image Text:Part 2: Molecular Weights The molecular weight of a large polymer such as a nucleic acid or a polypeptide depends on the length of the polymer. The monomers (nucleotides or amino acids) vary in molecular weight, but for a long polymer you can just use the average mass of a monomer, according to the table below: Double-stranded DNA (dsDNA) 618 Daltons/nucleotide pair Single-stranded DNA (ssDNA) 309 Daltons/nucleotide Single-stranded RNA (ssRNA) 320 Polypeptide 110 Daltons/nucleotide Daltons/amino acid Daltons are more or less the same as the atomic mass units you use in chemistry class: 1 Dalton 1 gram/mole Since macromolecules are large, the actual units used are usually kilo Daltons (KD). For the following questions, show your calculations. Use scientific notation where appropriate, and use appropriate units (micrograms, nanograms, etc). Round off your answers to three significant figures. a) Green Fluorescent Protein (GFP) is composed of a single polypeptide, 238 amino acids long. What is the approximate molecular weight of GFP in KD? b) What is the approximate molecular weight (in KD) of the coding region of the mRNA that encodes GFP? c) What is the approximate molecular weight of the corresponding double-stranded coding region of the DNA? d) What is the approximate ratio of the molecular weight of the coding region of the DNA to the molecular weight of the protein it encodes? (Show ALL your calculations on a piece of paper, take a picture and paste it in the space below).
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