Oropharyngeal cancer is a disease in which malignant (cancer) cells form in the tissues of the oropharynx. The gold standard to diagnose this disease is through RNA qPCR. In 2011, Schache et al. determined the accuracy of Human Papilloma Virus p16 immunohistochemistry (p16 IHC) in detection of oropharyngeal carcinoma. Results from 200 patients are shown in the table below: see photo Compute for the sensitivity of p16 IHC in diagnosis of oropharyngeal carcinoma. Source: Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., ... & Sloan, P. (2011). Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clinical Cancer Research, 17(19), 6262-6271. 82.0% 83.9% 93.2% 94.0%
Oropharyngeal cancer is a disease in which malignant (cancer) cells form in the tissues of the oropharynx. The gold standard to diagnose this disease is through RNA qPCR. In 2011, Schache et al. determined the accuracy of Human Papilloma Virus p16 immunohistochemistry (p16 IHC) in detection of oropharyngeal carcinoma. Results from 200 patients are shown in the table below: see photo Compute for the sensitivity of p16 IHC in diagnosis of oropharyngeal carcinoma. Source: Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., ... & Sloan, P. (2011). Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clinical Cancer Research, 17(19), 6262-6271. 82.0% 83.9% 93.2% 94.0%
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
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Question
Oropharyngeal cancer is a disease in which malignant (cancer) cells form in the tissues of the oropharynx. The gold standard to diagnose this disease is through RNA qPCR.
In 2011, Schache et al. determined the accuracy of Human Papilloma Virus p16 immunohistochemistry (p16 IHC) in detection of oropharyngeal carcinoma. Results from 200 patients are shown in the table below:
see photo
Compute for the sensitivity of p16 IHC in diagnosis of oropharyngeal carcinoma.
Source: Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., ... & Sloan, P. (2011). Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clinical Cancer Research, 17(19), 6262-6271.
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82.0% |
||
|
83.9% |
||
|
93.2% |
||
|
94.0% |
Transcribed Image Text:p16 IHC Test
Positive
Negative
TOTAL
Oropharyngeal Squamous
Cell Carcinoma Status
(by RNA qPCR)
Present
Absent
94
18
6
82
100
100
112
88
200
TOTAL
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