——— oooo and ——— located on the vesicle, promote the binding of vesicles to the target membrane. v-SNARE, tethering proteins SNAPS, NSF v-SNARE, t-SNARE tethering proteins, SNAPS Rab GTPase, v-SNARE
In order for molecules to move across the many membrane-enclosed compartments of the secretory pathway, transport vesicles are essential. Thus, a key cellular function known as vesicular transport is in charge of moving molecules between a range of distinct membrane-enclosed compartments. Therefore, it is essential for preserving the cell's functional organization that such transport is selective. For instance, lysosomal enzymes must specifically be delivered from the Golgi apparatus to lysosomes—not to the plasma membrane or the ER. Several of the signals direct proteins to particular organelles, including lysosomes. Due to the fact that these proteins are transported within vesicles, the specificity of transport is predicated on the careful packing of the intended cargo into vesicles that only recognize and fuse with the proper target membrane.
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