One form of posttranscriptional modification of most eukaryoticpre-mRNAs is the addition of a poly-A sequence at the 3' end. Theabsence of a poly-A sequence leads to rapid degradation of thetranscript. Poly-A sequences of various lengths are also added tomany bacterial RNA transcripts where, instead of promoting stability,they enhance degradation. In both cases, RNA secondarystructures, stabilizing proteins, or degrading enzymes interactwith poly-A sequences. Considering the activities of RNAs, whatmight be general functions of 3'-polyadenylation?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
One form of posttranscriptional modification of most eukaryotic
pre-mRNAs is the addition of a poly-A sequence at the 3' end. The
absence of a poly-A sequence leads to rapid degradation of the
transcript. Poly-A sequences of various lengths are also added to
many bacterial RNA transcripts where, instead of promoting stability,
they enhance degradation. In both cases, RNA secondary
structures, stabilizing proteins, or degrading enzymes interact
with poly-A sequences. Considering the activities of RNAs, what
might be general functions of 3'-polyadenylation?
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