O-linked glycosylation occurs on ___ residues of proteins. a) Serine and Threonine b) Asparagine c) Methionine d) Acidic amino acid residues

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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O-linked glycosylation occurs on ___ residues of proteins.

a) Serine and Threonine
b) Asparagine
c) Methionine
d) Acidic amino acid residues
Expert Solution
Step 1
  • The attachment of sugar moieties to protein forms glycoprotein.
  • It is one of the post-translation modifications of a protein that occurs after its translation.
  • The reaction is catalyzed by the enzyme glycosyltransferases.
  • Nearly half of the proteins that are expressed in the cell undergo this modification.
  • There are different types of glycosylation:

         a. N-linked

         b. O-linked

         c. Glypiation

         d. C-linked

         e. Phosphoglycosylation

 

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