Neurotransmitters, the chemicals used in signaling across synapses, can be either re-absorbed by the pre-synaptic neuron OR hydrolyzed after release by enzymes.  Acetylcholine (ACh), the neurotransmitter at neuromuscular junctions, is broken down by the enzyme acetylcholinesterase (AChE) and then its component parts are re-absorbed. Sarin gas is an extremely dangerous neurotoxin that has been utilized in terrorism and chemical warfare.  It is known as a "nerve gas" because it blocks AChE.  Based on your understanding of the neuromuscular junction and hydrolitic enzymes, hypothesize how sarin gas le ads to paralysis and nerve damage in the people to whom it is exposed.

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