Which statement is true regarding GABA and Glutamate? Glutamate signaling is only required for the development of glutamatergic synapses O GABA is always inhibitory Glutamate is recycled with the aid of glial cells at the synapse O Neither glutamate nor GABA are very prevalent in the CNS

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**Understanding GABA and Glutamate in the Central Nervous System**

**Quiz Question:**
Which statement is true regarding GABA and Glutamate?

1. O Glutamate signaling is only required for the development of glutamatergic synapses
2. O GABA is always inhibitory
3. O Glutamate is recycled with the aid of glial cells at the synapse
4. O Neither glutamate nor GABA are very prevalent in the CNS

**Explanation:**

This question is designed to test your knowledge of the roles of GABA (Gamma-Aminobutyric Acid) and glutamate in the central nervous system (CNS). Each option provides a statement regarding the nature and function of these neurotransmitters.

1. **Glutamate signaling is only required for the development of glutamatergic synapses**
   - Glutamate is the main excitatory neurotransmitter in the CNS. It is involved in synaptic plasticity, which is crucial for learning and memory, beyond just the development of glutamatergic synapses.

2. **GABA is always inhibitory**
   - GABA is indeed the primary inhibitory neurotransmitter in the CNS, playing a crucial role in reducing neuronal excitability and maintaining a balance with excitatory signals.

3. **Glutamate is recycled with the aid of glial cells at the synapse**
   - After functioning in synaptic transmission, glutamate is taken up by surrounding glial cells (astrocytes) and converted to glutamine, which neurons can then reuse to synthesize more glutamate.

4. **Neither glutamate nor GABA are very prevalent in the CNS**
   - Both glutamate and GABA are highly prevalent in the CNS. Glutamate acts as the primary excitatory neurotransmitter, while GABA serves as the chief inhibitory neurotransmitter, making them essential for proper neural function.

Choose the correct option to consolidate your understanding of neurotransmitter functions in the CNS.
Transcribed Image Text:**Understanding GABA and Glutamate in the Central Nervous System** **Quiz Question:** Which statement is true regarding GABA and Glutamate? 1. O Glutamate signaling is only required for the development of glutamatergic synapses 2. O GABA is always inhibitory 3. O Glutamate is recycled with the aid of glial cells at the synapse 4. O Neither glutamate nor GABA are very prevalent in the CNS **Explanation:** This question is designed to test your knowledge of the roles of GABA (Gamma-Aminobutyric Acid) and glutamate in the central nervous system (CNS). Each option provides a statement regarding the nature and function of these neurotransmitters. 1. **Glutamate signaling is only required for the development of glutamatergic synapses** - Glutamate is the main excitatory neurotransmitter in the CNS. It is involved in synaptic plasticity, which is crucial for learning and memory, beyond just the development of glutamatergic synapses. 2. **GABA is always inhibitory** - GABA is indeed the primary inhibitory neurotransmitter in the CNS, playing a crucial role in reducing neuronal excitability and maintaining a balance with excitatory signals. 3. **Glutamate is recycled with the aid of glial cells at the synapse** - After functioning in synaptic transmission, glutamate is taken up by surrounding glial cells (astrocytes) and converted to glutamine, which neurons can then reuse to synthesize more glutamate. 4. **Neither glutamate nor GABA are very prevalent in the CNS** - Both glutamate and GABA are highly prevalent in the CNS. Glutamate acts as the primary excitatory neurotransmitter, while GABA serves as the chief inhibitory neurotransmitter, making them essential for proper neural function. Choose the correct option to consolidate your understanding of neurotransmitter functions in the CNS.
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