Need help Explain the consequence of the following mutation on the function of the corresponding proteins. A) In hemoglobin, His HC3 mutates to Glu (account for all the interactions that HC3 makes). B) In Mb, His F8 mutates to Trp. C) In fetal hemoglobin, Ser 143 mutates to Asp.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Need help
Explain the consequence of the following mutation on the function of the corresponding proteins.
A) In hemoglobin, His HC3 mutates to Glu (account for all the interactions that HC3 makes).
B) In Mb, His F8 mutates to Trp.
C) In fetal hemoglobin, Ser 143 mutates to Asp.
D) In a-keratin fibrils, 80% of Lys and Glu were replaced with Ala and leu, respectively.
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