Mutant strains of Helicobacter pylori that lack the ability to produce urease fail to cause infection when they are swallowed. Infection occurs, however, if a tube is used to introduce them directly into the layer of mucus that overlies the stomach epithelium. What does this imply about the role of urease in the bacterium’s pathogenicity?
Pathogenicity
Infection and Transmission
The infections are generated by the pathogenic organisms present in the environment. They maintain the capacity to invade a host body and establish colonies. A disease caused by such infectious agents is called a communicable disease or transmissible disease. These diseases spread through diverse means including blood, food, water, air, or vectors.
Mutant strains of Helicobacter pylori that lack the ability to produce urease fail to cause infection when they are swallowed. Infection occurs, however, if a tube is used to introduce them directly into the layer of mucus that overlies the stomach epithelium. What does this imply about the role of urease in the bacterium’s pathogenicity?
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