After a man infected with a Gram-negative bacterium was treated with the correct antibiotic for this pathogen, the bacterium was no longer found in the man’s blood, but his symptoms of fever and inflammation worsened. What caused the man’s response to the treatment? Why was his condition worsened by the treatment?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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After a man infected with a Gram-negative bacterium was treated with the correct antibiotic for this
pathogen, the bacterium was no longer found in the man’s blood, but his symptoms of fever and
inflammation worsened. What caused the man’s response to the treatment? Why was his condition
worsened by the treatment?

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Step 1

E. coli is a gram-negative bacterium which cell wall is composed of a thin, inner layer of peptidoglycan and an outer membrane. The outer membrane of the gram-negative cell wall consists of phospholipids, lipopolysaccharides (LPS), lipoproteins, and surface proteins.

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