Match the following terms with their correct definitions.A change in a gene thatcauses it to produce noprotein.A loss-of-funtion in oneallele that is uominantbecause the wild type allelealone does not produceenough protein to serve itstypical role.1. Loss-of-function mutation2. Null mutation3. Gain-of-function mutationA change in a gene thatcauses it to produce lessprotein or protein that isnot able to serve its typicalrole.4. HaploinsufficiencyA change in a gene thatcauses it to produceincreased protein or proteinthat takes on a new role.

Name: Match the following terms with their correct definitions.A change in
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Description: Match the following terms with their correct definitions.A change in a gene thatcauses it to produce noprotein.A loss-of-funtion in oneallele that is uominantbecause the wild type allelealone does not produceenough protein to serve itstypical role.1

Answered: Match the following terms with their…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Match the following terms with their correct definitions.
A change in a gene that
causes it to produce no
protein.
A loss-of-funtion in one
allele that is uominant
because the wild type allele
alone does not produce
enough protein to serve its
typical role.
1. Loss-of-function mutation
2. Null mutation
3. Gain-of-function mutation
A change in a gene that
causes it to produce less
protein or protein that is
not able to serve its typical
role.
4. Haploinsufficiency
A change in a gene that
causes it to produce
increased protein or protein
that takes on a new role.

Expert Solution

Step 1

Activating mutations in proto-oncogenes that cause growth. Protooncogenes are the genes which causes cause cancer, activating such genes is gain of function of the protein.

Mutations in tumor suppressor genes that lead to cancer. Tumor suppressor genes are the genes which prevents cancer by producing proteins which checks the cell cycle regularly. If mutation happened in that region, it is a loss of the functional protein. It loses its function to prevent the cell cycle growth if any damage occurs.

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