Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of K'q and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate Kéq for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Kg = 1.8 x10-6 Incorrect Calculate the mass-action ratio, Q , from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = 3 fructose 6-phosphate 81.0 fructose 1,6-bisphosphate 15.0 Incorrect ATP 12,500 ADP 1,340
Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of K'q and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate Kéq for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Kg = 1.8 x10-6 Incorrect Calculate the mass-action ratio, Q , from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = 3 fructose 6-phosphate 81.0 fructose 1,6-bisphosphate 15.0 Incorrect ATP 12,500 ADP 1,340
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Kéq and Q,
the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium.
The equation for this equilibrium is,
fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP
Calculate Kg for this reaction at T = 25.0 °C.
Ka
1.8 x10-6
AG' = -14.2 kJ/mol
Incorrect
Calculate the mass-action ratio, Q, from the approximate physiological concentrations for rat heart tissue shown in
the table.
Metabolite
Concentration (µM)
Q = 3
fructose 6-phosphate
81.0
fructose 1,6-bisphosphate
15.0
Incorrect
ATP
12,500
ADP
1,340
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