MAKE CONNECTIONS The bacterium Wolbachia is asymbiont that lives in mosquito cells and spreads rapidlythrough mosquito populations. Wolbachia can make mosquitoes resistant to infection by Plasmodium; researchersare seeking a strain that confers resistance and does notharm mosquitoes. Compare evolutionary changes thatcould occur if malaria control is attempted using such aWolbachia strain versus using insecticides to kill mosquitoes. (Review Figure 28.16 and Concept 23.4.)

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