It was later discovered in Cliff Tabin’s lab that a gene called Bmp4 involved in cell-cell signaling during beak development is partly responsible for beak depth in ground finches (Abzhanov et al., 2004).  Alleles that increase Bmp4 expression increase the depth of the beaks, and were most likely selected for during the drought in 1977 (Abzhanov et al., 2004).  In 2001, ground finches were collected from Daphne major and genotypes were analyzed at this particular locus.   Phenotype Genotype Number of Individuals Observed Genotype Frequency Low Bmp4 expression AA 491 ? Low Bmp4 expression Aa 336 ? High Bmp4 expression aa 552 ?                                                 In 2009, allele frequencies were measured again on Daphne major for this particular gene.  Phenotype Genotype Number of Individuals Observed Genotype Frequency Low Bmp4 expression AA 706 ? Low Bmp4 expression Aa 493 ? High Bmp4 expression aa 129

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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  1. It was later discovered in Cliff Tabin’s lab that a gene called Bmp4 involved in cell-cell signaling during beak development is partly responsible for beak depth in ground finches (Abzhanov et al., 2004).  Alleles that increase Bmp4 expression increase the depth of the beaks, and were most likely selected for during the drought in 1977 (Abzhanov et al., 2004).  In 2001, ground finches were collected from Daphne major and genotypes were analyzed at this particular locus.

 

Phenotype

Genotype

Number of Individuals

Observed Genotype Frequency

Low Bmp4 expression

AA

491

?

Low Bmp4 expression

Aa

336

?

High Bmp4 expression

aa

552

?

                                               

In 2009, allele frequencies were measured again on Daphne major for this particular gene. 

Phenotype

Genotype

Number of Individuals

Observed Genotype Frequency

Low Bmp4 expression

AA

706

?

Low Bmp4 expression

Aa

493

?

High Bmp4 expression

aa

129

?

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