For the fish model organism Medaka (Aplocheilus latipes), genes at 2 loci (B, b and R, r) determine color of the fish. Fish that have the dominant allele at both loci (B_ R_) are brown, fish with a dominant allele at the B locus (B_ rr) are blue, fish with a dominant allele at the R locus only (bb R_) are red, and fish that are homozygous recessive at both loci (bb rr) are white. What is the expected phenotypic ratio of offspring of cross between a homozygous brown and homozygous white Medaka fish? What is the expected phenotypic ratio of offspring if you then generate an F2 generations from the progeny above? Assume that you performed the cross and you observed 465 brown fish, 142 blue fish, 165 red fish, and 61 white fish in the F2 generation. Use a chi-square test to compare the observed and expected numbers of offspring. What conclusions can you draw from your statistical analysis of these results?

Human Anatomy & Physiology (11th Edition)
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For the fish model organism Medaka (Aplocheilus latipes), genes at 2 loci (B, b and R, r) determine color of the fish. Fish that have the dominant allele at both loci (B_ R_) are brown, fish with a dominant allele at the B locus (B_ rr) are blue, fish with a dominant allele at the R locus only (bb R_) are red, and fish that are homozygous recessive at both loci (bb rr) are white.

  1. What is the expected phenotypic ratio of offspring of cross between a homozygous brown and homozygous white Medaka fish?
  2. What is the expected phenotypic ratio of offspring if you then generate an F2 generations from the progeny above?
  3. Assume that you performed the cross and you observed 465 brown fish, 142 blue fish, 165 red fish, and 61 white fish in the F2 generation. Use a chi-square test to compare the observed and expected numbers of offspring. What conclusions can you draw from your statistical analysis of these results?
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