In addition to C. elegans and Drosophila, Zebrafish are also another model organism - and have a spine. We're interested in two phenotypes, a curved spine and a gene that causes skin tumors to form on the fish's skin. We'd like to know if we could use the curved spine as an indicator if a fish may develop tumors (if the genes are linked). We'll assume that each of these traits is controlled by a single gene where: a curved spine is the result of a dominant allele S (and a normal spine is the result of recessive alleless), ⚫ and tumor growth is the result of a recessive allele t (and no tumor growths are a dominant T allele). A testcross is performed with a fish that is heterozygous for both genes and the resulting progeny are given below. TtSs x ttss curved spine & no tumors curved spine & tumors normal spine & no tumors 27 45 normal spine & tumors 30 SUN 50 Are these two genes following Mendelian inheritance patterns? Use Chi-Squared analysis to test them. x2 = (0-6)² 1. X2 value: type your answer... 2. Degrees of Freedom: type your answer.... Table 11.5 Chi-Square Probabilities Probabilities df 0.95 0.90 0.70 0.50 0.30 0.20 0.10 0.05 0.01 0.001 1 0.004 0.016 0.15 0.46 1.07 1.64 2.71 3.84 6.64 10.83 3. p-value type your answer... 2 0.10 0.21 0.71 1.39 2.41 3.22 4.61 5.99 9.21 13.82 3 0.35 0.58 1.42 2.37 3.67 4.64 6.25 7.82 11.35 16.27 4 0.71 1.06 2.20 3.36 4.88 5.99 7.78 9.49 13.28 18.47 4. Determination: YES they appear mendelian, or NO they appear to be non-mendelian type your answer... 5 1.15 1.61 3.00 4.35 6.06 7.29 9.24 11.07 15.09 20.52 1.64 2.20 3.83 5.35 7.23 8.56 10.65 12.59 16.81 22.46 5. Assume for a moment that these genes are linked. If so, what allele combinations are parental in the TtSs genotype listed in the cross? type your answer...
In addition to C. elegans and Drosophila, Zebrafish are also another model organism - and have a spine. We're interested in two phenotypes, a curved spine and a gene that causes skin tumors to form on the fish's skin. We'd like to know if we could use the curved spine as an indicator if a fish may develop tumors (if the genes are linked). We'll assume that each of these traits is controlled by a single gene where: a curved spine is the result of a dominant allele S (and a normal spine is the result of recessive alleless), ⚫ and tumor growth is the result of a recessive allele t (and no tumor growths are a dominant T allele). A testcross is performed with a fish that is heterozygous for both genes and the resulting progeny are given below. TtSs x ttss curved spine & no tumors curved spine & tumors normal spine & no tumors 27 45 normal spine & tumors 30 SUN 50 Are these two genes following Mendelian inheritance patterns? Use Chi-Squared analysis to test them. x2 = (0-6)² 1. X2 value: type your answer... 2. Degrees of Freedom: type your answer.... Table 11.5 Chi-Square Probabilities Probabilities df 0.95 0.90 0.70 0.50 0.30 0.20 0.10 0.05 0.01 0.001 1 0.004 0.016 0.15 0.46 1.07 1.64 2.71 3.84 6.64 10.83 3. p-value type your answer... 2 0.10 0.21 0.71 1.39 2.41 3.22 4.61 5.99 9.21 13.82 3 0.35 0.58 1.42 2.37 3.67 4.64 6.25 7.82 11.35 16.27 4 0.71 1.06 2.20 3.36 4.88 5.99 7.78 9.49 13.28 18.47 4. Determination: YES they appear mendelian, or NO they appear to be non-mendelian type your answer... 5 1.15 1.61 3.00 4.35 6.06 7.29 9.24 11.07 15.09 20.52 1.64 2.20 3.83 5.35 7.23 8.56 10.65 12.59 16.81 22.46 5. Assume for a moment that these genes are linked. If so, what allele combinations are parental in the TtSs genotype listed in the cross? type your answer...
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:In addition to C. elegans and Drosophila, Zebrafish are also another model organism - and have a spine. We're interested in two phenotypes, a curved spine and a gene that
causes skin tumors to form on the fish's skin. We'd like to know if we could use the curved spine as an indicator if a fish may develop tumors (if the genes are linked). We'll
assume that each of these traits is controlled by a single gene where:
a curved spine is the result of a dominant allele S (and a normal spine is the result of recessive alleless),
⚫ and tumor growth is the result of a recessive allele t (and no tumor growths are a dominant T allele).
A testcross is performed with a fish that is heterozygous for both genes and the resulting progeny are given below.
TtSs x ttss
curved spine & no tumors
curved spine & tumors
normal spine & no tumors
27
45
normal spine & tumors
30
SUN
50
Are these two genes following Mendelian inheritance patterns? Use Chi-Squared analysis to test them. x2 = (0-6)²
1. X2 value: type your answer...
2. Degrees of Freedom: type your answer....
Table 11.5 Chi-Square Probabilities
Probabilities
df
0.95
0.90
0.70
0.50
0.30
0.20
0.10
0.05
0.01
0.001
1
0.004
0.016
0.15
0.46
1.07
1.64
2.71
3.84
6.64
10.83
3. p-value type your answer...
2
0.10
0.21
0.71
1.39
2.41
3.22
4.61
5.99
9.21
13.82
3
0.35
0.58
1.42
2.37
3.67
4.64
6.25
7.82
11.35
16.27
4
0.71
1.06
2.20
3.36
4.88
5.99
7.78
9.49
13.28
18.47
4. Determination: YES they appear mendelian, or NO they appear to be non-mendelian
type your answer...
5
1.15
1.61
3.00
4.35
6.06
7.29
9.24
11.07
15.09
20.52
1.64
2.20
3.83
5.35
7.23
8.56
10.65
12.59
16.81
22.46
5. Assume for a moment that these genes are linked. If so, what allele combinations are parental in the TtSs genotype listed in the cross? type your answer...
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