In the fish Species a, the expression of different combinations of four Hox genes results in structural differences in tissues and organs along the anterior-posterior axis. Figure 3 shows the expression pattern of four genes, i.e. Genes 1 – 4, and the tissue produced along the embryonic anterior - posterior plane of fish Species a wild type. The influence of Hox genes on the formation of specific types of tissue can be determined by introducing gain-of-function and loss-of-function mutations in specific Hox genes. Looking at Figure 3, predict what would happen to each one of the four types of tissues, if the expression of gene 3 was expanded anteriorly by a gain-of-function mutation so that the pattern of gene 3 expression would be the same as that of gene 2.
Transcribed Image Text:### Gene Expression Across Different Tissue Types
**Figure 3:**
This bar graph illustrates the expression levels of four distinct genes (Gene 1, Gene 2, Gene 3, Gene 4) across four different tissue types, labeled W, X, Y, and Z. The tissue types are arranged from anterior (top) to posterior (bottom).
- **Gene 1**: Exhibits the highest expression in tissue type W.
- **Gene 2**: Shows substantial expression in tissue type X, although it falls short of Gene 1’s expression in tissue type W.
- **Gene 3**: Demonstrates a moderate level of expression in tissue type Y.
- **Gene 4**: Displays the lowest expression among the sampled genes, with measurable levels only in tissue type Z.
Understanding the spatial and quantitative differences in gene expression is crucial for studies in developmental biology, as it helps elucidate how genes contribute to the formation and function of different tissues in an organism. Each gene's distinct pattern of expression provides insights into its specific role within these tissue types.
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