Removing the patch of tissue called the ZPA from one limb bud and placing into onto another developing limb bud with an intact ZPA results in the digits being duplicated in a mirror image fashion. Which of the following best explains what this revealed regarding the way digit formation is determined?     A) The gradient of a gene product emanating from within the ZPA tissue determines digit differentiation, such that low concentrations form the thumb homologue, high concentrations the pinky.     B) The ZPA tissue includes all of the genetic blueprints necessary for digit formation, having two ZPAs resulted in twice the gene product, thus two sets of digits, rather than one.     C) The ZPA is not responsible for controlling the development of digits.     D) None of the above.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Removing the patch of tissue called the ZPA from one limb bud and placing into onto another developing limb bud with an intact ZPA results in the digits being duplicated in a mirror image fashion. Which of the following best explains what this revealed regarding the way digit formation is determined?

   

A) The gradient of a gene product emanating from within the ZPA tissue determines digit differentiation, such that low concentrations form the thumb homologue, high concentrations the pinky.

   

B) The ZPA tissue includes all of the genetic blueprints necessary for digit formation, having two ZPAs resulted in twice the gene product, thus two sets of digits, rather than one.

   

C) The ZPA is not responsible for controlling the development of digits.

   

D) None of the above.

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