In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?   The yellow pigment produced by A allele is required for survival. The AY allele lacks an upstream merc gene which is required for normal embryonic development. The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual. The AY allele contains a null mutation in the A gene, which is required for normal embryonic development. None of the other answers are correct.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?
 
The yellow pigment produced by A allele is required for survival.
The AY allele lacks an upstream merc gene which is required for normal embryonic development.
The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual.
The AY allele contains a null mutation in the A gene, which is required for normal embryonic development.
None of the other answers are correct.
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