Inferring incomplete penetrance FIGURE 6-21 In this human pedigree of a dominant allele that is not fully penetrant, person Q does not display the phenotype but passed the dominant allele to at least two progeny. Because the allele is not fully penetrant, the other progeny (for example, R) may or may not have inherited the dominant allele.
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In Figure 6-21, propose a specific genetic explanation
for individual Q (give a possible genotype, defining the
alleles
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Solved in 2 steps
- LABORATORY EXERCISES IN GENETICS a. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Duchenne Muscular Dystrophy? are most likly made op intentence for Duchenne Miscular Rysty Uale b. If couple III-7 and IlI-8 have another child, what is the probability that the child will have Duchenne Muscular Dystrophy? c. If IlI-2 and IlI-7 mated, what is the probability that one of their children would have the disease?Analysis of X-Linked Dominant and Recessive Traits Suppose a couple, both phenotypically normal, have two children: one unaffected daughter and one son affected with a genetic disorder. The phenotype ratio is 1:1, making it difficult to determine whether the trait is autosomal or X-linked. With your knowledge of genetics, what are the genotypes of the parents and children in the autosomal case? In the X-linked case?Equalizing the Expression of X Chromosome Genes in Males and Females Individuals with an XXY genotype are sterile males. If one X is inactivated early in embryogenesis, the genotype of the individual effectively becomes XY. Why will this individual not develop as a normal male?
- F1 hybrids between two species of cotton, Gossypium barbadenseand Gossypium hirsutum, are very vigorous plants. However, F1crosses produce many seeds that do not germinate and a high percentageof very weak F2 offspring. Suggest two reasons for theseobservations.Classes SBI3C1-2 rr x rr Meet - rz pQLSeUir31BTTSeUl8EYpVNYpajrmzBg_g0n6oMivineMfM4k0w/viewform rr x Rr Classwork O Rrx Rr ORR X Rr Genet X SBI3C1-2 Genetics Two parents were known to be right-handed. Assuming that right-handed (R) is dominant to left-handed (r), what would be the genotypes of the parents if their son is left-handed? Google M Post Atte Sp * 1 poirFAlpQLSfiOhfAvlhxzCSiUll_6rt-nU5b0WI73UmWOxkOw8OCwk01ng/formResponse B 1 2 Bb x Bb b 4 The fur in both parents in this cross is * 1 B B Bb x Bb b 3 4 brown black O homozygous dominant homozygous recessive 3. 近
- Monohybrid Problems llustrating Codominamce 5. Another type of monohybrid inheritance involves the expression of both phenotypes in the heterozy- gous situation. This is called codominance. One well-known example of codominance occurs in the coat color of Shorthorn cattle. Those with reddish-gray roan coats are heterozygous (RR'), and result from a mating between a red (RR) Shorthorn and one that's white (R'R'). Roan cattle don't have roan-colored hairs, as would be expected with incom- plete dominance, but rather appear roan as a result of having both red and white hairs. Thus, the roan col- oration is not a consequence of pigments blending in each hair. Because the R and R' alleles are both fully expressed in the heterozygote, they are codominant. a. If a roan Shorthorn cow is mated with a white bull, what will be the genotypic and phenotypic ratios in the F, generation? genotypic ratio . phenotypic ratio b. List the parental genotypes of crosses that could produce at least some…dd-ons Help в I U A Calibri 12 三 三1 |:三 6. Consider a guinea pig with a homozygous genotype and a white fur color phenotype. a. What is the probability this parent will produce a gamete with the dominant allele? b. What is the probability this parent will produce a gamete with the recessive allele? C. If 31 sperm cells are collected from this guinea pig, how many would you expect to have the recessive allele (as determined by sequencing the gene)? !!!11:52 and ry bod es loc he al alle omi Tomo tted es, wh Show cemplete nis ne n the type ratios for each generatio pes an Other problems: How do you know the genotype of organisms with a dominant phenotype? Is it homozygous or heterozygous? 8. A pea plant exhibits a purple color, but you are unsure of its genotype. With what could you cross this plant to determine its genotype? Show all of your work for the cross. What is this type of cross called? Incomplete dominance: Genes code for the production of specific proteins, many of which are enzymes. Different alleles at a locus code for alternative forms of a protein that differ in structure and when the protein is an enzyme, often have different degrees of catalytic activity. Therefore, a heterozygote genotvpe produces an intermediate phenotype.
- Bb Take Test: Mod 9 Lab - Genetic X + ← ] C G QUESTION 3 In the pedigree below, all shaded individuals express the gene in question. For example, Arlene "has" the trait, she displays the phenotype in question. For example, if we were following the inheritance pattern of a widow's peak, Arlene has a widow's peak (that is NOT the trait here, just an example). Unshaded individuals (blank circles and squares) do not manifest the trait in question, but their specific genotype is unknown - they could be heterozygous, homozygous dominant, or homozygous recessive. What is the mechanism of inheritance of this trait? Sandra Daniel recessive dominant Tom 990 Alan QUESTION 4 George Sam Tina Christopher Arlene Wilma Ann O Carla R Update Michael In the pedigree below, all shaded individuals express the gene in question. For example, Arlene "has" the trait, she displays the phenotype in question. For example, if we were following the inheritance pattern of a widow's peak, Arlen a widow's peak (that…ybrid Cross - Parental (P) vill be observing the F, offspring of the cross shown in nage. The purple colof (P) of the kernel is the result of ment called anthocyanin, which is dominant and not nked. /hat are the genotypes of the F, offspring if both nts shown are homozygous? F1 Mendel's dihybrid cross always showed a the same ratio ONLY for traits that are not linked on the same mosome and inherited together. If the genes are linked the ratio will not follow Mendel's dihybrid ratio. What is atio seen in dihybrid crosses that are not linked? F2 EXPERIMENTAL QUESTION: Are the genes for color (P) and shape (R) linked (on the same chromosome)?3.27 Complementation tests of the recessive mutant g genes a through f produced the data in the accom- panying matrix. The circles represent missing data. beaim Assuming that all of the missing mutant combina- motions would yield data consistent with the entries ithat are known, complete the table by filling each oneel circle with a + or – as needed. - rt yd bat 21 igi a rıb a O + b c d e fi 612 nobsdi b liw insiqans bosale yns mon las 29 ni YOu C ono e 66 BA AA f AA