inal illness that is accompanied by intense pain. As a first atter thesis, he conducts an experiment in which 16 rats are randomly ps of eight each. Animals in the experimental group receive a small l e thalamus thought to be involved with pain perception. Animals in th ive a comparable lesion in a brain area believed to be unrelated to p furgon gach animal is given a brief electrical shock to the nawe

MATLAB: An Introduction with Applications
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2. A neurosurgeon believes that lesions in a particular area of the brain, called the
thalamus, will decrease pain perception. If so, this could be important in the treatment of
terminal illness that is accompanied by intense pain. As a first attempt to test this
hypothesis, he conducts an experiment in which 16 rats are randomly divided into two
groups of eight each. Animals in the experimental group receive a small lesion in the part
of the thalamus thought to be involved with pain perception. Animals in the control group
receive a comparable lesion in a brain area believed to be unrelated to pain. Two weeks
after surgery, each animal is given a brief electrical shock to the paws. The shock is
administered in an ascending series, beginning with a very low intensity level and
increasing until the animal first flinches. In this manner, the pain threshold to electric shock
is determined for each rat. The following data are obtained. Each score represents the
current level (milli-amperes) at which flinching is first observed. The higher the current
level is, the higher is the pain threshold. Note that one animal died during surgery and
was not replaced.
Neutral Area Lesions
Thalamic Lesions
1.9
0.8
0.7
1.8
1.2
1.6
0.5
1.5
0.4
1.0
0.9
0.9
1.4
1.7
1.1
Is there any decrease pain perception on the lesions of the thalamus?
Transcribed Image Text:2. A neurosurgeon believes that lesions in a particular area of the brain, called the thalamus, will decrease pain perception. If so, this could be important in the treatment of terminal illness that is accompanied by intense pain. As a first attempt to test this hypothesis, he conducts an experiment in which 16 rats are randomly divided into two groups of eight each. Animals in the experimental group receive a small lesion in the part of the thalamus thought to be involved with pain perception. Animals in the control group receive a comparable lesion in a brain area believed to be unrelated to pain. Two weeks after surgery, each animal is given a brief electrical shock to the paws. The shock is administered in an ascending series, beginning with a very low intensity level and increasing until the animal first flinches. In this manner, the pain threshold to electric shock is determined for each rat. The following data are obtained. Each score represents the current level (milli-amperes) at which flinching is first observed. The higher the current level is, the higher is the pain threshold. Note that one animal died during surgery and was not replaced. Neutral Area Lesions Thalamic Lesions 1.9 0.8 0.7 1.8 1.2 1.6 0.5 1.5 0.4 1.0 0.9 0.9 1.4 1.7 1.1 Is there any decrease pain perception on the lesions of the thalamus?
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