In the diagram below, the orange circle represents an effector and the dark purple shapes (both the diamond and the rod) represent a substrate. Based on this information, which statement(s) about the diagram is/are true? Select all that apply. A Allosteric site B Allosteric site C Allosteric site Allosteric effector Active site Allosteric effector Active site, Allosteric effector Novel binding site

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
- [ ] In panel B, the effector induces a conformational change that inhibits enzyme activity.

- [ ] The effector regulates enzyme activity by binding to the active site.

- [ ] In panel A, the effector induces a conformational change that inhibits enzyme activity.

- [ ] In panel B, the effector induces a conformational change that enhances enzyme activity.

- [ ] The effector regulates enzyme activity by binding to the substrate.

- [ ] In panel A, the effector induces a conformational change that enhances enzyme activity.
Transcribed Image Text:- [ ] In panel B, the effector induces a conformational change that inhibits enzyme activity. - [ ] The effector regulates enzyme activity by binding to the active site. - [ ] In panel A, the effector induces a conformational change that inhibits enzyme activity. - [ ] In panel B, the effector induces a conformational change that enhances enzyme activity. - [ ] The effector regulates enzyme activity by binding to the substrate. - [ ] In panel A, the effector induces a conformational change that enhances enzyme activity.
**Diagram Explanation: Allosteric Effector and Substrate Binding**

This diagram illustrates the interaction of an allosteric effector with an enzyme, highlighting the effect on substrate binding. The orange circle represents the allosteric effector, while the dark purple shapes (a diamond and a rod) symbolize substrates.

**Diagram A:**
- The enzyme is shown with an allosteric site and an active site. 
- The allosteric effector can bind to the allosteric site, which alters the enzyme's conformation. 
- Upon binding, the substrate (depicted as a diamond) can fit into the active site.

**Diagram B:**
- Similar to Diagram A, the effector binds to the allosteric site.
- However, in this configuration, the substrate (shown as a rod) does not fit into the active site, indicating a change in substrate specificity or enzyme activity.

**Diagram C:**
- The binding of the allosteric effector creates a novel binding site rather than utilizing the original active site. 
- This configuration suggests the formation of a new area on the enzyme where substrates can bind.

**Educational Focus:**
These diagrams demonstrate how allosteric effectors can influence enzyme activity, specificity, and function by altering the configuration of binding sites. Understanding these interactions is crucial for studying enzyme regulation and metabolic pathways.
Transcribed Image Text:**Diagram Explanation: Allosteric Effector and Substrate Binding** This diagram illustrates the interaction of an allosteric effector with an enzyme, highlighting the effect on substrate binding. The orange circle represents the allosteric effector, while the dark purple shapes (a diamond and a rod) symbolize substrates. **Diagram A:** - The enzyme is shown with an allosteric site and an active site. - The allosteric effector can bind to the allosteric site, which alters the enzyme's conformation. - Upon binding, the substrate (depicted as a diamond) can fit into the active site. **Diagram B:** - Similar to Diagram A, the effector binds to the allosteric site. - However, in this configuration, the substrate (shown as a rod) does not fit into the active site, indicating a change in substrate specificity or enzyme activity. **Diagram C:** - The binding of the allosteric effector creates a novel binding site rather than utilizing the original active site. - This configuration suggests the formation of a new area on the enzyme where substrates can bind. **Educational Focus:** These diagrams demonstrate how allosteric effectors can influence enzyme activity, specificity, and function by altering the configuration of binding sites. Understanding these interactions is crucial for studying enzyme regulation and metabolic pathways.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON