Which of the following statements regarding enzymes and transition states is true?stabilization of the transition state must be less than stabilization of ES forcatalysis to occurbinding of substrate to an enzyme often causes strain, thus promoting transitionstate formationthe transition state conformation of an enzyme catalyzed reaction is identical to theconformation seen in the uncatalyzed transition stateformation of the transition state always assures that the reaction will proceed toproductnone of the above are true

Introduction: Catalysis is an important function of an enzyme. For any chemical reaction to occur,…

Answered: Which of the following statements…

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Which of the following statements regarding enzymes and transition states is true?

stabilization of the transition state must be less than stabilization of ES for

catalysis to occur
binding of substrate to an enzyme often causes strain, thus promoting transition

state formation
the transition state conformation of an enzyme catalyzed reaction is identical to the

conformation seen in the uncatalyzed transition state
formation of the transition state always assures that the reaction will proceed to

product
none of the above are true