In E. coli, a methyltransferase enzyme encoded by the dam generecognizes the sequence 5′–GATC–3′ and attaches a methyl groupto the nitrogen at position 6 of adenine. E. coli strains that have thedam gene deleted are known to have a higher spontaneous mutationrate than normal strains. Explain why.

Q: Certain repeated sequences in eukaryotes are flanked by short direct repeats, suggesting that they…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: DNA in human mitochondria encodes 22 different tRNA molecules. However, 32 different tRNA molecules…

A: Mitochondrial gene expression maintain cellular homoeostasis. Mitochondrial gene expression is…

Q: A glycine residue is in position 210 of the tryptophan synthetase enzyme of wild-type E. coli. If…

A: Single base substitutions in which change in only one base pair occurs.

Q: Referring to the genetic code presented in Figure , give the aminoacids specified by the following…

A: Codons: The mRNA sequence reads the nucleotides (three nucleotides are considered as a group…

Q: Describe the anticodon of a single tRNA that could recognize the codons 5′–AAC–3′ and 5′–AAU–3′.…

A: Ribonucleic acid (RNA) is a nucleic acid found in both the nucleus and cytoplasm. It can be genetic…

Q: A eukaryotic gene has two introns and three exons. The first intron closest to the promoter is 157…

A: To draw the structure of the hybridized mRNA and estimate the size of the protein coded for by this…

Q: People with a commonly occurring, wild type allele of PTC with two adjacent thymines at a particular…

A: Part a.) :-ans.The presence of two adjacent thymines at a specific site in the PTC coding sequence…

Q: A certain ochre suppressor inserts glutamine in response to the ochre codon. What is the most likely…

A: In this scenario, where a suppressor mutation allows the insertion of glutamine instead of…

Q: The following DNA nucleotides are found near the end of a bacterial transcription unit.…

A: Introduction Gene expression can only occur when the Gene is transcribed into mRNA and then this…

Q: Several experiments were conducted to obtain information about how the eukaryotic ribosome…

A: Gene expression is a process by which the genes are turned on to form RNA and proteins. This is seen…

Q: Calculate the expected number of times that a given 8-base-pair DNA site should be present in the E.…

A: A bacterial genomic DNA resides inside cells in a highly condensed and functionally organized form…

Q: The DNA of a deletion of alpha bacteriophage has a length of 15 micrometers instead of 17…

A: The bacteriophage is those viruses that have the capability to infect bacteria and reproduce inside…

Q: The following polynucleotide was synthesized and used as a template forpeptide synthesis in a…

A: The consecutive three nucleotides together form one codon. Each codon encodes for a particular amino…

Q: DNA polymerase I (Pol I) of E. coli consists of three functional parts (domains): an N-terminal…

A: Molecular Biology is the branch of biology that deals with a study of the composition, arrangement,…

Q: The antibacterial protein colicin E3 is an effective inhibitor of protein synthesis in bacteria.…

A: Colicins are produced by some strains of E. coli that carries colicinogenic plasmid having genetic…

Q: Considering that prokaryote genomes do not have large introns, how is it possible to move a…

A: Technically, a eukaryotic gene may be transferred into a modified bacteria via genetic engineering…

Q: Eukaryotes modify mRNA with an m7G cap: an  N7-methylated guanosine linked via a 5′ to 5′…

A: The capping of mRNA is a mechanism that prevents the mRNA strand from being degraded by exonucleases…

Q: Determine the mRNA sequence for the wild type polypeptide by identifying the codons that correspond…

A: Polypeptides are chain of amino acids which is bonded by the peptide bonds. It is coded from the…

Q: Consider the now dominant variant of the SARS-CoV-2 called the D614G mutation: a) The mutation…

A: mRNA is translated to form protein. mRNAs contain trinucleotides sequences that code for particular…

Q: Methylated CpG dinucleotides are hotspots for point mutations in human DNA. Can you propose a…

A: Spontaneous deamination of 5 methyl cytosine produce thymine. When its and corrected it causes…

Q: A transposable element is found to encode a reverse transcriptase enzyme. On the basis of this…

A: Transposable elements are known as stretches of DNA molecules and they can move from one place to…

Q: MCAD deficiency is an inborn error of metabolism. The coding strand is shown for the wild-type gene.…

A: DNA (deoxyribonucleic acid) is a double stranded molecule. One strand present in the 5’ to 3’…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.