In breast cells, the BRCA1 and BRCA2 genes are highly expressed during the G1/S checkpoint. The G1/S checkpoint allows the cell to proceed to the G2 phase and cell division. monitors attachment of spindle fibers to chromosomes. O monitors completion of DNA synthesis. O monitors DNA damage before DNA replication.

Q: Describe what happens to the G1 cell cycle check point of a skin cell that is stimulated to divide…

A: Transformation of cells from one phase of the cell cycle to another is controlled by some external…

Q: After DNA damage (e.g. caused by X-ray exposure) in eukaryotic cells, the cell cycle can be arrested…

A: The protein cyclin and CDK (cyclin-dependent protein kinase) act together to drive the process of…

Q: Modify the diagram above to illustrate specific protein(s) that would participate in regulating this…

A: RB retinoblastoma gene is a tumor suppressor gene.

Q: Explain the function of the G₁, G₂ and metaphase checkpoints.

A: The cell actually stays in interphase mostly. When it is prepared for growth & chromosomal…

Q: Cell division cycle (cdc) mutations identify genes, the normal products of which are..…

A: Gene Function: CDC mutations pinpoint genes that are vital for regulating the cell division cycle.…

Q: Insulin-like growth factor (IGF) is a peptide hormone (ligand) that binds and activates IGF receptor…

A: Receptor Tyrosine Kinase (RTK) is an enzyme that belongs to the family of enzymes known as  protein…

Q: Which of the following is false about cyclin-cdk complexes? Cdk's do not have to bind to cyclin…

A: Cdk/cyclin complexes phosphorylates proteins required to trigger next cell cycle phase - this…

Q: Which of the following would result in cell cycle arrest? O phosphorylation of Rb by G1-Cdk…

A: It is a stopping point in the cell cycle,  where it is no longer involved in the processes…

Q: Somatic stem cells are found in...   all choices are correct       embryonic tissues       adult…

A: somatic stem cell are found in adult ,sometime somatic stem cell also called adult stem cell .Where…

Q: Describe the mammalian cell cycle briefly. In your work, include a description of how cyclins and…

A: The duplication and differentiation of cells are controlled by a assortment of genes. To guarantee…

Q: f the anaphase promoting complex (APC) is temperature sensitive (active at 30C, but inactive at…

A: Anaphase-promoting complex is an E3 ubiquitin ligase that marks target cell cycle proteins for…

Q: Which is true about cyclin B levels and/or activity?     increasing during anaphase     high…

A: Answer of the question given below...

Q: How does p53 halt cell cycle progression when DNA damage is identified? p53 enhances expression of…

A: p53 protein is a transcription factor that regulates the expression of several genes which are…

Q: Which of the following would lead to increased progression through the G1/S cell cycle check point?…

A: Check point : it is a stage where cells examine the internal and external cues , and take a decision…

Q: // Which one of these does CDK1/cyclin mitotic kinase NOT do to induce mitosis? Phosphorylates…

A: ANSWER;- a) Phosphorylates Histone H1 to condense chromosomes Explain;-The cyclin B-Cdk1 kinase…

Q: Which of the following statement(s) about cyclins is false? O Cyclins bind to cyclin dependent…

A: Cyclins concentration changes during the cell cycle. Cyclins are a family of proteins. Their…

Q: Discuss two-three ways that kinases/phosphatases OR proteasomes ensures proper rates of cell…

A: In order for duplicated chromosomes to bind appropriately to spindle microtubules and partition…

Q: // Which CDK and cyclin does p53 ultimately target in DNA damaged conditions? O CDK1/cyclin E O…

A: CDK phosphorylate soecific target proteins. They required cyclin to be activate. CDK-cyclin…

Q: allów it to move past the G1 and G2 checkpoints even if its growth factor is not present, These…

A: Whenever cells come into contact with each other, the mechanism of contact inhibition occurs. As a…

Q: Senescent cells usually undergo marked changes in chromatin structure characterized by densely…

A: Cellular senescence is the loss of a cell's capacity to divide and function normally.This can be a…

Q: In other words, the master regulator initiates a program of gene expression that narrow the…

A: Cell signalling

Q: Labels Differentiated and specialized Immortal Nuclei take up most of the cell Attach to substrate…

A: Cancer cells are rapidly dividing cells. As a result they form a lump of cells.  Rapid division…

Q: What are growth factors, and what role do they play in the control (or loss of control) of the cell…

A: Growth factors as the name suggest are responsible for the growth of certain body tissues s and thus…

Q: In attempting to design a drug that will impede cell cycle progression in ovarian cancers cells. you…

A: The answer is none of these.The cell cycle is a tightly regulated process that controls the growth…

Q: The cell enters g1 and cyclin D binds with CDK4/6  Increases in cyclin D expression prevent p21/p27…

A: cell cycle goes through following steps in a sequence:-

Q: An environmental change can lead to the production of more than the expected amount of cyclin in G1.…

A: If cyclins are produced in larger amounts, cyclin-dependent kinases are activated in large amounts.…

Q: Radiation therapy is commonly used in the treatment of cancer because it interferes with the…

A: Ans: Radiation therapy: The use o X-rays for killing cancer cells as a part of cancer treatment is…

Q: TRUE / FALSE (if false put the correct word in) Voltage-gated sodium channels open to allow the…

A: Sodium channels are present in the integral membrane.It helps the flow of Na+ ions within the cell.…

Q: Radiation, which induces DNA damage, inhibits cancer progression by:     Breaking down Rb…

A: Radiation, which induces DNA damage, inhibits cancer progression by activating p53.

Q: p53 gene, as is the Rb gene, is a tumor suppressor gene.  p53 protein binds to DNA leading to the…

A: p53 activates various responses, including cell-cycle arrest and apoptosis. Each of these appears to…