I 2 II 5 III 10 11 12 13 14 15 16 17 6 4 9 (7 8 A BC 7,8 C 1,2 600 2 5,6 4 4,6 6 9 7,9 7,8 2 1,2 1 69 7809 4 9 7,8 2 2 47 9 2 661 7,8 6801 4 4,6 9 8,9 7 69 67 4,6 6 5,6 7,8 8 8,9 47 2 1,2 1 1 1 1 1,2 3

Essentials Health Info Management Principles/Practices
4th Edition
ISBN:9780357191651
Author:Bowie
Publisher:Bowie
Chapter7: Numbering & Filing Systems And Record Storage & Circulation
Section: Chapter Questions
Problem 17CR
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Question

In dogs, three STRP loci are linked on the long arm of the X chromosome (in the order centromere-
A-B-C-telomere). In the pedigree shown below, each individual was genotyped for the 3 markers
and bands identified on a gel are shown beneath each individual.
a. Why do males always have just one allele at each locus? Why do females sometimes have one
and sometimes have two?
b. Which individuals have recombinant haplotypes?
c. For each recombinant individual in generation III, identify where the recombination events took
place (between which loci AND in which parent).
d. Draw a map showing the genetic distances between the three loci, based on the information
you have

I
2
II
5
III
10 11 12 13 14 15 16 17
6
4
9
(7 8
A
BC
7,8
C
1,2
600 2
5,6 4 4,6 6
9
7,9 7,8
2
1,2
1
69
7809
4
9
7,8
2
2
47
9
2
661
7,8
6801
4 4,6
9
8,9 7
69
67
4,6
6 5,6
7,8
8 8,9
47
2 1,2
1
1
1
1
1,2 3
Transcribed Image Text:I 2 II 5 III 10 11 12 13 14 15 16 17 6 4 9 (7 8 A BC 7,8 C 1,2 600 2 5,6 4 4,6 6 9 7,9 7,8 2 1,2 1 69 7809 4 9 7,8 2 2 47 9 2 661 7,8 6801 4 4,6 9 8,9 7 69 67 4,6 6 5,6 7,8 8 8,9 47 2 1,2 1 1 1 1 1,2 3
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