Humans and chimpanzees share about 98% of their DNA. What is DNA? What might be the role of regulatory genes in producing the anatomical differences between these two lineages? Give two examples of how the field of genetics has revolutionized biological science. What is polymerase chain reaction (PCR) and why is it important in genetics?
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- Now that cloning is possible, should it be used to clone animals that are near extinction? What are the possible ramifications of this when it comes to genetic diversity and size of the gene pool?Bioinformatics is an interdisciplinary field that integrates knowledge of computer science with mathematics and statistics to solve biological questions. Many bioinformatics tools for gene prediction, homology modelling and such are available free online. (1) What does BLAST stand for? (ii) Explain the function of BLAST.What are some of the technical challenges of cloning a mammoth? Check all that are true Ancient mammoth DNA has degraded so it is hard to know the complete genome sequence Mammoth gestation time is likely too short to allowing cloning A living surrogate mother would have to be used, which could pose problems since the closest relative to mammoths is endangered elephants A living oocyte would have to be obtained from an extant species, which could pose problems since the closest relative to mammoths is endangered elephants Mammoths lived so long ago that they used a different genetic code than modern animals There are no enzymes in existence that could ligate together mammoth DNA sequence with elephant sequence Mammoths probably had egg shells, which would be hard to penetrate with a needle
- Bioinformatics is the science of using computational methods (specialized software) to decipher the biological meaning of information contained within an organismal system. If you have to identify a gene, for example from the fruit fly, that is of interest to you, and you would like to know whether the human genome contains a homolog (related gene) of the fruit fly gene, one tool you could use is a program called Group of answer choices RefSeq (species reference sequence) Excel BLAST (Basic Local Alignment Search Tool) GenBankWooly Mammoths have been extinct for about 10,000 years; however, their remains have been well persevered in Siberia. Due to global warming, these remains are now available to be recovered. Scientists want to extract the DNA and through cloning insert the DNA into an elephant to clone the mammoth. What are some of the pros and cons of cloning an extinct animal?Write a paragraph describing the evolutionary forces driving changes in the human genome. You can include evolutionary forces such as random genetic drift, mutation, migration, and natural selection. These forces would have long-term and short-term effects on coding and non-coding DNA, the abundance of transposable elements, and the birth and death of genes. You can focus on a subset of the human population, or the entire species.
- How does molecular biology paved way for the development of the DNA fingerprinting technique? and what is its molecular basis?Is gene transfer a form of eugenics? Is it advantageous to use gene transfer to eliminate some genetic disorders? Can this and other technology be used to influence the evolution of our species? Should there be guidelines for the use of genetic technology to control its application to human evolution? Who should create and enforce these guidelines?The Human Genome Project has demonstrated that in humans of all races and nationalities approximately 99.9 percent of the sequence is the same, yet different individuals can be identified by DNA fingerprinting techniques. What is one primary variation in the human genome that can be used to distinguish different individuals? Briefly explain your answer.
- Many animals have the p53 gene that makes a protein that regulates the cell cycle and helps prevent the formation of cancer cells. The table below shows the percentage of p53 gene sequences that the 4 species have when compared to humans. Species Percentage of p53 Gene Sequence Similar to Human Human 100 Horse 60.7 Fruit Fly 15.5 Rat 76.8 Pig 81.3 Which organism in the table is most closely related to humans based on this data? pig horse fruit fly rat 0 0 0 0Cloning is the process of creating genetically identical organisms. One simple method of cloning is called artificial embryo twinning. In this process, an early stage embryo is separated into two groups of cells. Each group of cells is then allowed to develop. The embryos are then implanted into the surrogate mother. Each embryo is genetically identical to the other. Some pregnancies in humans have a similar result. Explain how identical twins are formed. Compare and contrast the natural formation of identical twins to the artificial embryo twinning process. Explain how the formation of identical twins or the process of artificial embryo twinning differs from the formation of fraternal twins.You just graduated from college and started working at a biotech startup called Scrofabulous. Your first job assignment is to clone the pig gene for the hormone prolactin. Assume that the pig gene for prolactin has not yet been isolated, sequenced, or mapped; What would be the most useful and economical first step to go about identifying and cloning the pig gene for prolactin? use the amino acid sequence of mouse prolactin to design a pair of degenerate oligonucleotide PCR primers to PCR-amplify the pig prolactin gene. RNAseq the pituitary gland of the pig, the most abundant gene is likely to to be prolactin Conduct a proteome search for peptides that match parts of mouse prolactin protein Sequence the pig genome, then translate the genome to find the gene predicted to encode for prolactin Crystalize the mouse prolactin protein and use Google's DeepMind Al to find the closest amino acid sequence in the pig proteome