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Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell1. You are studying a spherical eukaryotic cell that has a diameter of 20 µm and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na'glucose symporters distrībuted throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of (5.000x101) μMhr Based on this number, how many umoles of glucose must be entering the cell per hour? (Assume that one-half of the volume of the cell is composed of organelles, and thus not available for diffusion of glucose). Put your final answer in umol/hr.

Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell1. You are studying a spherical eukaryotic cell that has a diameter of 20 µm and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na'glucose symporters distrībuted throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of (5.000x101) μMhr Based on this number, how many umoles of glucose must be entering the cell per hour? (Assume that one-half of the volume of the cell is composed of organelles, and thus not available for diffusion of glucose). Put your final answer in umol/hr.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell. You are studying a spherical eukaryotic cell that has a diameter of 20 μm and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na/glucose symporters distributed throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of (5.000x10^1) μM/hr. Based on this number, how many μmoles of glucose must be entering the cell per hour? (Assume that one-half of the volume of the cell is composed of organelles, and thus not available for diffusion of glucose). Put your final answer in μmol/hr.
Transcribed Image Text:Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell. You are studying a spherical eukaryotic cell that has a diameter of 20 μm and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na/glucose symporters distributed throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of (5.000x10^1) μM/hr. Based on this number, how many μmoles of glucose must be entering the cell per hour? (Assume that one-half of the volume of the cell is composed of organelles, and thus not available for diffusion of glucose). Put your final answer in μmol/hr.
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