A scientist has noticed that the phospholipid, phosphatidylethanolamine, displays an asymmetric distribution in the cell membrane. Where would you MOST likely predict to find a concentration of phosphatidylethanolamine? O In the cytosolic face of a transport vesicle leaving the trans Golgi network. O In the cytosolic face of a transport vesicle leaving the endoplasmic reticulum. O In the non-cytosolic face of a late endosome fusing to the lysosome.

A scientist has noticed that the phospholipid, phosphatidylethanolamine, displays an asymmetric distribution in the cell membrane. Where would you MOST likely predict to find a concentration of phosphatidylethanolamine? O In the cytosolic face of a transport vesicle leaving the trans Golgi network. O In the cytosolic face of a transport vesicle leaving the endoplasmic reticulum. O In the non-cytosolic face of a late endosome fusing to the lysosome.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Name the three groups into which membrane-associated proteins may be classified. Explain the mechanism by which each group associates with a biomembrane.
According to the “Hawaiian Punch” principle, different compartments of the secretory and endocytic pathways are topologically equivalent to each other and to the extracellular space. Explain how vesicular transport generates this topological equivalence. These compartments are topologically equivalent because molecules can move between them without having to move out of the cell. Transport vesicles cause this “topological equivalence” because they are responsible for the actual movement of the molecules mentioned above. They break off from one compartment, carrying the necessary molecules, and then fuse to its targeted compartment; thus, making the compartments topologically equivalent. During mitosis in mammalian cells, the nuclear envelope breaks down into vesicles. Are the topological properties of the cell altered by this event? Justify your answer.
would substances be able to pass through the plasma membrane if the phospholipi tails of the plasma membrane were oth satueated fatty acids? why or why not, explain?
Ammonia (NH3) is a weak base that under acidic conditions becomes protonated to the ammonium ion in the following reaction: NH3 + H+ → NH+4 NH3 freely permeates biological membranes, including those of lysosomes. The lysosome is a subcellular organelle with a pH of about 4.5–5.0; the pH of cytoplasm is about 7.0. What is the effect on the pH of the fluid content of lyso- somes when cells are exposed to ammonia? Note: Ammo- nium (NH4+) does not diffuse freely across membranes.
Which of the following statements is false? Integral membrane proteins cannot, in general, be extracted from a cell without disruption of the membranes. The portion of an integral membrane protein that traverses the membrane has, in general, hydrophobic amino acid residues on the surface and hydrophilic amino acid residues in the interior. Peripheral membrane proteins can often be extracted from a membrane surface using a buffer with a high [salt]. Proteins can be tethered to a membrane via a lipid prosthetic group. Unless attached to the cytoskeleton, membrane lipids diffuse about the membrane surface.
The antibiotic Gramicidin A can transport Na+ inons into a certain cell at the rate of 5.0 x 10 ^7 Na+ ion channel-1 s-1. Calculate the time in seconds it takes to transport enough Na+ ions to increases its concentration by 8.0 x10 -3 M in a cell whose intracellular volume is 2.0 x 10-10 mL
In the situations described below, what is the free energy change if 1 mole of Na+ is transported across a membrane from a region where the concentration is 48 μM to a region where it is 110 mM? (Assume T=37∘C.) When the transport is opposed by a membrane potential of 70 mV.
Suppose that a plant cell membrane is permeable with Na*, CI ions and H20, but not with proteins. In addition, it is assumed that 0.05 M Nacl aqueous solution is present outside the cell membrane, and 0.001 M of protein (P) is present inside. The protein is ionized to p, z = 20, and the opposite ion is CI". From this, calculate the theft potential that occurs between the cell membrane and the external solution in equilibrium. Assume that the activity coefficient of all ions is 1.0.
Where is the KV1.1 (a membrane protein) polypeptide synthesized in the cell? (word bank: cytoplasm, nucleus, rough ER, smooth ER, mitochondria) The amino acids that line the outside of the KV1.1 protein (i.e., those in contact with the phospholipid bilayer's fatty acids tails) are more likely to be _______(word bank: hydrophobic, hydrophilic) The KV1.1 protein utilizes __ transport to move the K+ ions across the membrane. (word bank: active, passive) This disease can be caused by missense mutations. In general, how specifically would a missense mutation affect the KV1.1 protein?
During an investigation on membrane transport, a researcher exposed bacterial cells to different concentrations of two different solutes: A and B. The rate of transport of each solute into cells isrepresented in the graphSolute ASolute BSolute ConcentrationWhich of the following best explains the greater rate of transport for solute A than for solute B at higher solute concentrations?A Solute A is being transported by simple diffusion, which does not rely on membrane proteins to control the rate of transportSolute A is being transported by active transport, which uses ATP and has higher rates of transport than passive transportSolute A is being transported by facilitated diffusion, which uses membrane proteins to increase the rate of transportRate of Transport
Drawn below is a schematic of a transmembrane protein. Extracellular Cell membrane Cytosolic side (a) From the list below, select the amino acid(s) that might by more common in the extracellular domain of this membrane protein and whose side- chain can form hydrogen bonds with the surrounding water molecules. Explain why you selected this option(s). Lysine Serine Phenylalanine Methionine (b) From the list below, select the amino acid(s) that would likely be found in the transmembrane/ membrane spanning domain of this protein and whose side- chain interacts with the lipid bilayer. Lysine Serine Phenylalanine Methionine
Which of the following proteins is categorized as a multi-pass transmembrane protein (also called the anion exchange protein, because it exchanges chloride and bicarbonate ions in red blood cells)? band 3.0 protein (in the red blood cell membrane) COX-1 (in the lumenal leaflet of the smooth endoplasmic reticulum) glycophorin A (in the red blood cell membrane) the Ras protein (lipid-linked to the inner plasma membrane) cytochrome c (in the mitochondrion)