8.TABLE 3.3 Catalytic Activity of a Variety of EnzymesEnzymeNonenzymatic t,2'Turnover number?Rate enhancement78,000,000 yr130,000 yr120 yr69,000 yr69 yr2.9 yr7.3 yr7 wk1.4 x 1075.6 x 10142.1 x 10126.0 x 10121.2 x 10122.8 x 10"1.9 x 10"3.9 x 10"1.0 x 10°1.9 x 107.7 x 104.6 x 1039OMP decarboxylaseStaphylococcal nuclease95Adenosine deaminase370AMP nucleosidase60Cylidine deaminasePhosphotriesteraseCarboxypeptidase AKetosteroid isomerase2992,10057866,000Triosephosphate isomeraseChorismate mutase1.9 d4,3007.4 hr5 sec501 x 10Carbonic anhydraseCyclophilin, human23 sec13,000"The time that would elapse for half the reactants to be converted to product in the absence of enzyme.The number of reactions catalyzed by a single enzyme molecule per second when operating at a saturating substrate concentration.The increase in reaction rate achieved by the enzyme-catalyzed reaction over the noncatalyzed reaction.Source: A. Radzicka and R. Wolfenden, Science 267:91, 1995. Copyright 1995. Reprinted with permission from AAAS.The following reaction occurs in the metabolic pathway known as glycolysis:Dihydroxyacetone Phosphate (DHAP) € → Glyceraldehyde-3-phosphate (GAP)The enzyme triose phosphate isomerase catalyzes this reaction in our cells.A) Assuming saturating levels of DHAP and a favorable AG value, how long would it take 100molecules of triose phosphate isomerase to produce 1 million molecules of GAP?

In Kcat of dihydroxyacetone phosphate in non- enzymatic condition is 4300 in 1.9days. Basically, on…

he following reaction occurs in the metabolic pathway known as glycolysis: Dihydroxyacetone Phosphate (DHAP) € → Glyceraldehyde-3-phosphate (GAP) The enzyme triose phosphate isomerase catalyzes this reaction in our cells. A) Assuming saturating levels of DHAP and a favorable AG value, how long would it take 100 molecules of triose phosphate isomerase to produce 1 million molecules of GAP?

he following reaction occurs in the metabolic pathway known as glycolysis: Dihydroxyacetone Phosphate (DHAP) € → Glyceraldehyde-3-phosphate (GAP) The enzyme triose phosphate isomerase catalyzes this reaction in our cells. A) Assuming saturating levels of DHAP and a favorable AG value, how long would it take 100 molecules of triose phosphate isomerase to produce 1 million molecules of GAP?

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

See similar textbooks

Similar questions

For the following enzymes (3-6) predict how the conditions will most likely affect the enzymes activity with one of the following and provide a 1 sentence explanation: a. increase activity b. decrease activity c. not likely to alter activity 3) alpha-ketoglutarate dehydrogenase complex binding to AMP when [AMP] is high. 4) phosphohexose isomerase binding NADH when [NADH] is high 5) phosphofructose-1 binding NAD+ when [NAD+] is high 6) pyruvate dehydrogenase complex binding to ATP when [ATP] is high
In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free- energy change (AG) of 23.8 kJ/mol. Under what cellular conditions will the free-energy change be negative, enabling the reaction to proceed spontaneously to form products? O In a cell where the concentrations of products and reactants yield a low value of the mass-action ratio Q ○ The reaction will not go to the right spontaneously under any conditions because the AG is positive ○ The reaction will proceed spontaneously to the right if there is a high concentration of products relative to the concentration of fructose 1,6-bisphosphate ○ The reaction will proceed spontaneously to the right if there is a high concentration of enzyme to catalyze the reaction O None of these conditions is sufficient
Consider the fructose-1,6-bisphosphatase reaction. Calculate the free energy change if the ratio of the concentrations of the products to the concentrations of the reactants is 23.7, and the temperature is 37.0 °C? AG" for the reaction is -16.7 kJ/mol. The constant R = 8.3145 J/(mol-K) AG= Number kJ/mol
The reaction in which glucose 6-phosphate (G6P) is converted to fructose 6-phosphate (F6P) is an example of an isomerization reaction. Notice that both molecules have the molecular formula C6H13O9P. The isomerization is catalyzed by glucose 6-phosphate isomerase. This is a reversible reaction in cells, with a moderately negative ΔG, but a very high activation energy. If you have a flask that contains a solution containing cellular concentrations of G6P and F6P, but no enzyme, how will the concentration of each molecule change over time?
Consider the following chemical equation whose delta(G) = 9kcal/mol: AC + BD ---> AB + CD what are the reactants and what are the products is this reaction spontaneous? How do you know? Is energy released or consumed by this reaction? If an enzyme, which catalyzes this reaction is added, what will happen to delta (G) If this reaction is coupled to another reaction, whose delta(G) is -12 kcal/mol, what will be the net delta(G) value? will the overall reaction be spontaneous
The standard Gibbs (free) energy of reaction (A,Gº') of the following reaction is equal to zero (at 25 °C and pH 7) pyruvate + aspartate Pyruvate, aspartate and L-alanine are mixed each at a concentration of 1 mM, without oxaloacetate. Calculate the molar concentrations of each compound when the reaction reaches equilibrium. oxaloacétate + L-alanine
The AG of the reaction C6H12O6 + 60₂ --> 6CO₂ + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P₁ --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number.