GLUTI deficiency syndrome (GLUTIDS) is a genetic disease caused by mutations in the GLUTI protein, which leads to reduced or impaired expression of glucose transporters on the blood-brain barrier. As a result, individuals with GLUTIDS often exhibit intellectual disabilities below the normal level. Based on the function of GLUTI on the blood-brain barrier, explain the possible causes of intellectual disabilities.

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Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.