Glutamic acid (1one of the 20 amino acids) has a side- chain carboxyl group (COOH, pKa = 4.3) as shown in Figures 4.7 and 4.8 a. Write the chemical equation for the dissociation of the side chain COOH. Label the weak acid and the conjugate base. b. The Henderson-Hasselbalch Equation (shown below) can be used to determine the ionization status of a weak acid: pH = pKa + log [base] Use the Henderson Hasselbalch equation to determine whether the glutamic acid side chain [acid] • carboxyl group is protonated or deprotonated at physiological pH.
Glutamic acid (1one of the 20 amino acids) has a side- chain carboxyl group (COOH, pKa = 4.3) as shown in Figures 4.7 and 4.8 a. Write the chemical equation for the dissociation of the side chain COOH. Label the weak acid and the conjugate base. b. The Henderson-Hasselbalch Equation (shown below) can be used to determine the ionization status of a weak acid: pH = pKa + log [base] Use the Henderson Hasselbalch equation to determine whether the glutamic acid side chain [acid] • carboxyl group is protonated or deprotonated at physiological pH.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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![Glutamic acid (1one of the 20 amino acids) has a side- chain carboxyl group (COOH, pKa = 4.3) as shown in
Figures 4.7 and 4.8
a. Write the chemical equation for the dissociation of the side chain COOH. Label the weak acid and the conjugate
base.
b. The Henderson-Hasselbalch Equation (shown below) can be used to determine the ionization status of a weak acid:
pH = pKa + log [base] Use the Henderson Hasselbalch equation to determine whether the glutamic acid side chain
[acid]
•
carboxyl group is protonated or deprotonated at physiological pH.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa5be52d7-969f-48e7-912c-c8af10a8f6da%2Fe4b3b2e4-29e0-4647-b7dc-a5bfcb8215f3%2Fpf7w1lr_processed.png&w=3840&q=75)
Transcribed Image Text:Glutamic acid (1one of the 20 amino acids) has a side- chain carboxyl group (COOH, pKa = 4.3) as shown in
Figures 4.7 and 4.8
a. Write the chemical equation for the dissociation of the side chain COOH. Label the weak acid and the conjugate
base.
b. The Henderson-Hasselbalch Equation (shown below) can be used to determine the ionization status of a weak acid:
pH = pKa + log [base] Use the Henderson Hasselbalch equation to determine whether the glutamic acid side chain
[acid]
•
carboxyl group is protonated or deprotonated at physiological pH.
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