Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. Unaffected X chromosome = X *Unaffected/No carrier-Normal 11 d 1 * 1 1 2 a) X-linked recessive 9 III 2 genotype (circle one): XY 2 3 11x12 4 ΧΑΧΑ 2 3 5 Xaya *4 6 7 8 b) X-linked dominant 11x12 오 XAY Xay

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 10QP: A proband female with an unidentified disease seeks the advice of a genetic counselor before...
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1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X-
linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of
this trait. Disease allele = XA or Xa, depending on mode of transmission of the disease respectively.
*Unaffected/No carrier-Normal
Unaffected X chromosome = X
I
11
* 1
2
1
2
3
a) X-linked recessive 11x12
III 2 genotype (circle one): XY
4
XAXA
2
3
5
Xaya
*4
6
7
8
b) X-linked dominant 11x12
XAY
Xay
Transcribed Image Text:1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xa, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I 11 * 1 2 1 2 3 a) X-linked recessive 11x12 III 2 genotype (circle one): XY 4 XAXA 2 3 5 Xaya *4 6 7 8 b) X-linked dominant 11x12 XAY Xay
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