1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X-linked recessive and b) X-linked dominant in order to determine what is the mode of transmission ofthis trait. Disease allele = XA or Xa, depending on mode of transmission of the disease respectively.*Unaffected/No carrier-NormalUnaffected X chromosome = XI11* 12123a) X-linked recessive 11x12III 2 genotype (circle one): XY4XAXA235Xaya*4678b) X-linked dominant 11x12XAYXay

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Description: 1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X-linked recessive and b) X-linked dominant in order to determine what is the mode of transmission ofthis trait. Disease allele = XA or Xa, depend

The mode of inheritance is the pattern by which the trait or a disorder, which is passed from one…

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Biology

Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. Unaffected X chromosome = X *Unaffected/No carrier-Normal 11 d 1 * 1 1 2 a) X-linked recessive 9 III 2 genotype (circle one): XY 2 3 11x12 4 ΧΑΧΑ 2 3 5 Xaya *4 6 7 8 b) X-linked dominant 11x12 오 XAY Xay

Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. Unaffected X chromosome = X Unaffected/No carrier-Normal 11 d 1 1 1 2 a) X-linked recessive 9 III 2 genotype (circle one): XY 2 3 11x12 4 ΧΑΧΑ 2 3 5 Xaya *4 6 7 8 b) X-linked dominant 11x12 오 XAY Xay

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 2QP: Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the...

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Concept explainers

Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.

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Question

1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X-
linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of
this trait. Disease allele = XA or Xa, depending on mode of transmission of the disease respectively.
*Unaffected/No carrier-Normal
Unaffected X chromosome = X
I
11
* 1
2
1
2
3
a) X-linked recessive 11x12
III 2 genotype (circle one): XY
4
XAXA
2
3
5
Xaya
*4
6
7
8
b) X-linked dominant 11x12
XAY
Xay

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II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked dominant and b) X-linked recessive in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I || III 1 1 2 a) X-linked recessive 9 III 6 genotype (circle one): XX * 1 2 3 11x12 4 ΧΑΧΑ 2 5 xaxa *4 6 7 8 b) X-linked dominant 11 x 12 오 XAX хах
1. The figure below shows a pedigree examining the presence of a genetic disorder across multiple generations of a family. Based off this figure, answer the following questions prompted: || IV 3 9 10 5 2 C 6 11 T 7 12 8 15 13 16 14 17 d) What is the genotype for individual #4 in this family pedigree? ||| c) Why are no family members identified as a carrier of this genetic disorder? Figure Key a) Using the figure key provided, identify which members of this family are affected by this genetic disorder in each generation. (Be sure to include sex and generation number for each individual identified). b) Is this an autosomal recessive, autosomal dominant, or sex-linked genetic disorder? Explain. Unaffected Female Unaffected Male Affected Female ||| Affected Male Female Carrier Male Carrier
1. The pedigree below shows the incidence of rare, autosomal dominant disorder called Ehlers-Danlos disease. The pedigree covers three generations of a particular family and also shows individual genotypes at a potential marker locus (M). a) Indicate the phase of all gen II and III individuals. DdM1M3 ddM2M6 II DDM3M6 ddM4M5 III DdMзM4 DdMЗМ5 DDM3M4 ddM3M5 DDM3M4 ddM5M6 DDM3M4 ddM4M6 ddM5M6 ddM5M6 b) Which, if any, of the gen III individuals are recombinants? c) Calculate the LOD score as a test of physical linkage between the marker (M) and the disease locus. d) What do you conclude about linkage between D and M?
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II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) Autosomal recessive and b) Autosomal dominant in order to determine what is the mode of transmission of this trait. Disease allele = a or A, depending on mode of transmission of the disease respectively. Your Punnett squares should reflect what you see in generation II. Circle the mode of transmission. Note: Observe the whole pedigree. I Circle the mode of transmission 1 III 6 genotype (circle one): AA Created by Dr. Susan A. Holechek for BIO 340 (2023) 2 1 2 3 4 a) Autosomal recessive 11 x 12 9 XªXa 2 3 5 6 Ở хаха *4 7 b) Autosomal dominant 11x12 8 Aa *Unaffected/No carrier-Normal AaAa
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Consider a couple: a woman who is homozygous for a recessive mutation that causes X-linked colorblindness, and a man with full color vision (he does not carry a copy of the mutation). a) What is the probability that a son of this couple will be colorblind? b) What is the probability that a daughter of the couple will be colorblind?