Given the active site drawn below, what would you expect to happen to the acidity of the K residue? The pka will decrease due to charge repulsion The pka will increase due to charge repulsion The pka will remain unchanged The pka will decrease due to charge stabilization The pK₂ will increase due to charge stabilization

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Chapter1: Chemical Foundations
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Given the active site drawn below, what would you expect to happen to the acidity of the K
residue?
The pK₂ will decrease due to charge repulsion
The pK₂ will increase due to charge repulsion
The pka will remain unchanged
The pK₂ will decrease due to charge stabilization
The pka will increase due to charge stabilization
Transcribed Image Text:Given the active site drawn below, what would you expect to happen to the acidity of the K residue? The pK₂ will decrease due to charge repulsion The pK₂ will increase due to charge repulsion The pka will remain unchanged The pK₂ will decrease due to charge stabilization The pka will increase due to charge stabilization
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